Gene Symbol | OSBPL5 |
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Entrez Gene | 114879 |
Alt Symbol | OBPH1, ORP5 |
Species | Human |
Gene Type | protein-coding |
Description | oxysterol binding protein-like 5 |
Other Description | ORP-5|OSBP-related protein 5|oxysterol-binding protein homolog 1|oxysterol-binding protein homologue 1|oxysterol-binding protein-related protein 5 |
Swissprots | Q9BZB0 B4DVB0 Q8N596 A6NJS8 Q54A90 Q9P1Z4 A6NDP0 Q9H0X9 |
Accessions | EAX02542 EAX02543 Q9H0X9 AB074006 BAB85686 AF331964 AAG53417 AF392453 AAL40666 AF410430 AAK98617 AK055617 BAG51544 AK056510 BAG51735 AK124919 BAG54112 AK293000 BAF85689 AK297475 BAG59896 AK301003 BAG62622 AK303205 BAG64295 AK309411 AL136918 CAB66852 AM392891 CAL37769 AM393424 CAL38302 BC017505 AAH17505 BC032646 AAH32646 BC039579 AAH39579 DC400863 XM_011519873 XP_011518175 NM_001144063 NP_001137535 NM_020896 NP_065947 NM_145638 NP_663613 |
Function | May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. {ECO:0000269|PubMed:21220512}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21220512}; Single-pass membrane protein {ECO:0000269|PubMed:21220512}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12504849, ECO:0000269|PubMed:21220512}. |
ORP-5 CRISPR/Cas9 KO Plasmid (h) - sc-410253 from Santa Cruz Biotechnology
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ORP-5 HDR Plasmid (h) - sc-410253-HDR from Santa Cruz Biotechnology
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ORP-5 Double Nickase Plasmid (h) - sc-410253-NIC from Santa Cruz Biotechnology
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ORP-5 Double Nickase Plasmid (h2) - sc-410253-NIC-2 from Santa Cruz Biotechnology
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ORP-5 CRISPR Activation Plasmid (h) - sc-410253-ACT from Santa Cruz Biotechnology
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ORP-5 CRISPR Activation Plasmid (h2) - sc-410253-ACT-2 from Santa Cruz Biotechnology
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ORP-5 Lentiviral Activation Particles (h) - sc-410253-LAC from Santa Cruz Biotechnology
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ORP-5 Lentiviral Activation Particles (h2) - sc-410253-LAC-2 from Santa Cruz Biotechnology
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ORP-5 siRNA (h) - sc-96769 from Santa Cruz Biotechnology
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ORP-5 shRNA Plasmid (h) - sc-96769-SH from Santa Cruz Biotechnology
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ORP-5 shRNA (h) Lentiviral Particles - sc-96769-V from Santa Cruz Biotechnology
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OSBPL5 RNAi - H00114879-R02 from Novus Biologicals
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MISSION® esiRNA - EHU085181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16162 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16162 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07696 from Sigma-Aldrich
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OSBPL5 siRNA (Human) - CRJ4400 from Cohesion Biosciences
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OSBPL5 RNAi - H00114879-R01 from Novus Biologicals
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shRNA set against Human OSBPL5 (NM_020896.3) - SHH368656 from Creative biogene
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OSBPL5 shRNA Plasmid (Human) - CHJ4400 from Cohesion Biosciences
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OSBPL5 miRNA 3'UTR clone - MiUTR3H-08684 from Creative biogene
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OSBPL5 miRNA 3'UTR clone - MiUTR3H-08685 from Creative biogene
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OSBPL5 miRNA 3'UTR clone - MiUTR3H-08686 from Creative biogene
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