UBE2J2
| Gene Symbol | UBE2J2 |
|---|---|
| Entrez Gene | 118424 |
| Alt Symbol | NCUBE-2, NCUBE2, PRO2121 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin-conjugating enzyme E2, J2 |
| Other Description | non-canonical ubiquitin-conjugating enzyme 2|ubiquitin conjugating enzyme 6|ubiquitin conjugating enzyme E2, J2|ubiquitin-conjugating enzyme E2 J2|ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)|yeast UBC6 homolog |
| Swissprots | Q504T9 Q96T84 A8MYC7 Q8N2K1 Q96N26 |
| Accessions | EAW56255 EAW56256 EAW56257 EAW56258 EAW56259 EAW56260 EAW56261 EAW56262 EAW56263 EAW56264 EAW56265 EAW56266 EAW56267 Q8N2K1 AF116687 AAF71107 AF296658 AAK52609 AK056065 BAB71086 AK075017 BAC11355 AK098803 AK291935 BAF84624 AL555293 AW411508 BC027728 BC052579 BC094777 AAH94777 BC104890 AAI04891 BC113430 AAI13431 BC143657 AAI43658 BE382927 BE515187 BG112933 BG499172 BG717336 BM544827 BM765278 BM794599 BM926567 BQ881730 HQ258753 ADR83504 XM_005244718 XP_005244775 XM_005244719 XP_005244776 XM_006710333 XP_006710396 XM_006710334 XP_006710397 XM_011540613 XP_011538915 XM_011540614 XP_011538916 XM_011540615 XP_011538917 XM_011540616 XP_011538918 XM_011540617 XP_011538919 XM_011540618 XP_011538920 NM_058167 NP_477515 NM_194315 NP_919296 NM_194457 NP_919439 NM_194458 NP_919440 NM_194316 |
| Function | Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity). {ECO:0000255|PROSITE-ProRule:PRU00388}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. |
| Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
UBE2J2 CRISPR/Cas9 KO Plasmid (h) - sc-405930 from Santa Cruz Biotechnology
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UBE2J2 HDR Plasmid (h) - sc-405930-HDR from Santa Cruz Biotechnology
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UBE2J2 Double Nickase Plasmid (h) - sc-405930-NIC from Santa Cruz Biotechnology
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UBE2J2 Double Nickase Plasmid (h2) - sc-405930-NIC-2 from Santa Cruz Biotechnology
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UBE2J2 CRISPR Activation Plasmid (h) - sc-405930-ACT from Santa Cruz Biotechnology
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UBE2J2 CRISPR Activation Plasmid (h2) - sc-405930-ACT-2 from Santa Cruz Biotechnology
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UBE2J2 Lentiviral Activation Particles (h) - sc-405930-LAC from Santa Cruz Biotechnology
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UBE2J2 Lentiviral Activation Particles (h2) - sc-405930-LAC-2 from Santa Cruz Biotechnology
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UBE2J2 siRNA (h) - sc-88839 from Santa Cruz Biotechnology
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UBE2J2 shRNA Plasmid (h) - sc-88839-SH from Santa Cruz Biotechnology
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UBE2J2 shRNA (h) Lentiviral Particles - sc-88839-V from Santa Cruz Biotechnology
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UBE2J2/UBC6 RNAi - H00118424-R04 from Novus Biologicals
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UBE2J2/UBC6 RNAi - H00118424-R03 from Novus Biologicals
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UBE2J2/UBC6 RNAi - H00118424-R01 from Novus Biologicals
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MISSION® esiRNA - EHU123311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22369 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22369 from Sigma-Aldrich
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UBE2J2 siRNA (Human) - CRJ4578 from Cohesion Biosciences
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UBE2J2/UBC6 RNAi - H00118424-R02 from Novus Biologicals
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UBE2J2 - MBS829620 from MyBioSource
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shRNA set against Human UBE2J2 (NM_194458.1) - SHH439032 from Creative biogene
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shRNA set against Human UBE2J2(NM_194315.1) - SHL111108 from Creative biogene
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shRNA set against Human UBE2J2(NM_058167.2) - SHL111122 from Creative biogene
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shRNA set against Human UBE2J2(NM_194315.1) - SHL111134 from Creative biogene
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shRNA set against Human UBE2J2(NM_194457.1) - SHL111168 from Creative biogene
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