Gene Symbol | Tat |
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Entrez Gene | 24813 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | tyrosine aminotransferase |
Other Description | L-tyrosine:2-oxoglutarate aminotransferase |
Swissprots | P04694 Q5EBB6 |
Accessions | CAA09309 EDL92520 EDL92521 EDL92522 EDL92523 P04694 BC089813 AAH89813 M18340 AAA42203 X02741 CAA26519 NM_012668 NP_036800 |
Function | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. {ECO:0000269|PubMed:1682164}. |
Tissue Specificity | Liver. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis, Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids |
CompoZr® Knockout ZFN Kit - CKOZFN63885 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND63885 from Sigma-Aldrich
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TAT siRNA (Rat) - CRR0309 from Cohesion Biosciences
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TAT - MBS8211746 from MyBioSource
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shRNA set against Rat TAT (NM_012668.2) - SHH423628 from Creative biogene
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Rat TAT siRNA - orb295158 from Biorbyt
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TAT shRNA Plasmid (Rat) - CHR0309 from Cohesion Biosciences
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TAT miRNA 3'UTR clone - MiUTR1R-07912 from Creative biogene
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