CD80

Gene Symbol	CD80
Entrez Gene	941
Alt Symbol	B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Species	Human
Gene Type	protein-coding
Description	CD80 molecule
Other Description	B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
Swissprots	P33681 Q5DTB0 Q5DTA9
Accessions	AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182
Function	Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed on activated B-cells, macrophages and dendritic cells.
Top Pathways	Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human B7-1 / CD80 Gene cDNA Clone - orb141968 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Mouse B7-1/CD80 (NP_033985) VersaClone cDNA - RDC1180 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human B7-1/CD80 (NP_005182) VersaClone cDNA - RDC1086 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human CD80/B7-1 Gene ORF cDNA clone in cloning vector - HG10698-G from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10698-ACR from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid - HG10698-UT from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10698-ACG from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10698-NH from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10698-NF from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10698-NM from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10698-CY from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10698-CF from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10698-CM from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10698-NY from Sino Biological Species Human

Human CD80/B7-1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10698-CH from Sino Biological Species Human

B7-1/CD80 - CL01190H01 from Elabscience Species Human Accession NM_005191.3

Human CD80 ORF clone(NM_005191.3) - CDCL183412 from Creative biogene Species Human

Cynomolgus Monkey B7-1/CD80 (XP_005548122) VersaClone cDNA - RDC1587 from R&D Systems Prices $199.00 Sizes 10 µg Species Monkey

Rat B7-1/CD80 (NP_037058) VersaClone cDNA - RDC1763 from R&D Systems Prices $199.00 Sizes 10 µg Species Rat

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