| Gene Symbol |
Pou3f1
|
| Entrez Gene |
192110
|
| Alt Symbol |
Oct-6, Otf6, Scip, Testes-1, Tst-1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
POU class 3 homeobox 1
|
| Other Description |
OTF-6|POU domain transcription factor SCIP|POU domain, class 3, transcription factor 1|octamer-binding protein 6|octamer-binding transcription factor 6|octoamer transcription factor-6|octomer-6|suppressed cAMP-inducible POU
|
| Swissprots |
P20267
|
| Accessions |
P20267 M63712 AAA42303 M72711 AAA42118 NM_138838 NP_620193
|
| Function |
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis. Both in normal development and in response to nerve transection, SCIP expression was transiently activated only during the period of rapid cell division that separates the premyelinating and myelinating phases of Schwann cell differentiation. In cotransfection assays, scip acted as a transcriptional repressor of myelin specific genes.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Neural tissues and testis.
|