Gene Symbol | SRMS |
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Entrez Gene | 6725 |
Alt Symbol | C20orf148, SRM, dJ697K14.1 |
Species | Human |
Gene Type | protein-coding |
Description | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
Other Description | tyrosine-protein kinase Srms |
Swissprots | Q9H3Y6 |
Accessions | EAW75261 Q9H3Y6 BC148643 AAI48644 BC153198 AAI53199 NM_080823 NP_543013 |
Function | Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. May be involved in proliferation or differentiation of keratinocytes in the skin. {ECO:0000269|PubMed:23822091}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23822091}. Note=Localizes to punctate cytoplasmic structures. |
Tissue Specificity | Highly expressed in most breast cancers (at protein level). |
SRMS CRISPR/Cas9 KO Plasmid (h) - sc-407407 from Santa Cruz Biotechnology
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SRMS HDR Plasmid (h) - sc-407407-HDR from Santa Cruz Biotechnology
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SRMS Double Nickase Plasmid (h) - sc-407407-NIC from Santa Cruz Biotechnology
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SRMS Double Nickase Plasmid (h2) - sc-407407-NIC-2 from Santa Cruz Biotechnology
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SRMS CRISPR Activation Plasmid (h) - sc-407407-ACT from Santa Cruz Biotechnology
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SRMS CRISPR Activation Plasmid (h2) - sc-407407-ACT-2 from Santa Cruz Biotechnology
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SRMS Lentiviral Activation Particles (h) - sc-407407-LAC from Santa Cruz Biotechnology
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SRMS Lentiviral Activation Particles (h2) - sc-407407-LAC-2 from Santa Cruz Biotechnology
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SRMS siRNA (h) - sc-63066 from Santa Cruz Biotechnology
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SRMS shRNA Plasmid (h) - sc-63066-SH from Santa Cruz Biotechnology
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SRMS shRNA (h) Lentiviral Particles - sc-63066-V from Santa Cruz Biotechnology
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SRMS RNAi - H00006725-R02 from Novus Biologicals
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MISSION® siRNA - SIHK2118 from Sigma-Aldrich
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MISSION® siRNA - SIHK2119 from Sigma-Aldrich
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MISSION® siRNA - SIHK2117 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20577 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20577 from Sigma-Aldrich
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SRMS siRNA (Human) - CRH4592 from Cohesion Biosciences
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SRMS - MBS8226295 from MyBioSource
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shRNA set against Human Srms (NM_080823.2) - SHH417884 from Creative biogene
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shRNA set against Human SRMS(NM_080823.2) - SHL034784 from Creative biogene
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Human SRMS siRNA - orb265094 from Biorbyt
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SRMS shRNA Plasmid (Human) - CHH4592 from Cohesion Biosciences
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SRMS miRNA 3'UTR clone - MiUTR1H-09908 from Creative biogene
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