Gene Symbol | HMX3 |
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Entrez Gene | 340784 |
Alt Symbol | NKX-5.1, NKX5.1, Nkx5-1 |
Species | Human |
Gene Type | protein-coding |
Description | H6 family homeobox 3 |
Other Description | homeo box (H6 family) 3|homeobox (H6 family) 3|homeobox protein H6 family member 3|homeobox protein HMX3|homeobox protein Nkx-5.1 |
Swissprots | A8MU06 A6NHT5 |
Accessions | A6NHT5 EAW49289 AW088771 NM_001105574 NP_001099044 |
Function | Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
HMX3 CRISPR/Cas9 KO Plasmid (h) - sc-415554 from Santa Cruz Biotechnology
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HMX3 HDR Plasmid (h) - sc-415554-HDR from Santa Cruz Biotechnology
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HMX3 Double Nickase Plasmid (h) - sc-415554-NIC from Santa Cruz Biotechnology
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HMX3 Double Nickase Plasmid (h2) - sc-415554-NIC-2 from Santa Cruz Biotechnology
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HMX3 CRISPR Activation Plasmid (h) - sc-415554-ACT from Santa Cruz Biotechnology
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HMX3 CRISPR Activation Plasmid (h2) - sc-415554-ACT-2 from Santa Cruz Biotechnology
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HMX3 Lentiviral Activation Particles (h) - sc-415554-LAC from Santa Cruz Biotechnology
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HMX3 Lentiviral Activation Particles (h2) - sc-415554-LAC-2 from Santa Cruz Biotechnology
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HMX3 RNAi - H00340784-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10186 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10186 from Sigma-Aldrich
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HMX3 siRNA (Human) - CRJ7365 from Cohesion Biosciences
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HMX3 - MBS8216078 from MyBioSource
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shRNA set against Human HMX3 (NM_001105574.1) - SHH313581 from Creative biogene
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Human HMX3 siRNA - orb277866 from Biorbyt
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HMX3 shRNA Plasmid (Human) - CHJ7365 from Cohesion Biosciences
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