RPGRIP1L

Gene Symbol RPGRIP1L
Entrez Gene 23322
Alt Symbol CORS3, FTM, JBTS7, MKS5, NPHP8, PPP1R134
Species Human
Gene Type protein-coding
Description RPGRIP1-like
Other Description RPGR-interacting protein 1-like protein|fantom homolog|nephrocystin-8|protein fantom|protein phosphatase 1, regulatory subunit 134
Swissprots A0PJ88 Q68CZ1 Q9Y2K8
Accessions EAW82810 Q68CZ1 AB023222 BAA76849 AK026552 AK093307 AK096333 AK304790 BAG65540 AK307929 AK308390 BC017977 AAH17977 BC136433 AAI36434 BM683568 BQ576116 BX340768 CD674885 CR749645 CAH18439 DA156084 DC423209 EF565106 R45454 XM_005255867 XP_005255924 XM_005255868 XP_005255925 XM_005255869 XP_005255926 XM_005255871 XP_005255928 XM_011522968 XP_011521270 XM_011522969 XP_011521271 XM_011522970 XP_011521272 XM_011522971 XP_011521273 XM_011522972 XP_011521274 XM_011522973 XP_011521275 XM_011522974 XP_011521276 XR_933260 NM_001127897 NP_001121369 NM_001308334 NP_001295263 NM_015272 NP_056087
Function Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:21685204}. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, tight junction. Note=In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions.
Tissue Specificity Ubiquitously expressed with relatively high level of expression in hypothalamus and islet. During early development, expressed in multiple organs including brain, eye, forelimb and kidney. {ECO:0000269|PubMed:17434869, ECO:0000269|PubMed:17558407, ECO:0000269|PubMed:17558409, ECO:0000269|PubMed:19464661}.

RPGRIP1L (E-14) - sc-165399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RPGRIP1L (N-15) - sc-165400 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RPGRIP1L antibody - ab91467 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RPGRIP1L antibody (ab91467) at 1/100 dilution + 293 cell line lysates at 35 µg

Anti-RPGRIP1L antibody - ab77615 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-RPGRIP1L antibody (ab77615) at 0.3 µg + human brain (cerebellum) lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-RPGRIP1L Antibody (aa1210-1222) - LS-C61788 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RPGRIP1L Antibody (N-Terminus) - LS-C345714 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of FTM Antibody with human 293T Whole Cell lysate.

Anti-RPGRIP1L Antibody - LS-C332708 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HEK-293 cell line, using RPGRIP1L antibody.

RPGRIP1L Antibody - NBP1-84403 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Antibody - NBP1-00236 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody - bs-11946R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11946R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11946R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11946R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11946R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, Cy3 Conjugated - bs-11946R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, Cy5 Conjugated - bs-11946R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, Cy5.5 Conjugated - bs-11946R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, Cy7 Conjugated - bs-11946R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, FITC Conjugated - bs-11946R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, Biotin Conjugated - bs-11946R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L Polyclonal Antibody, HRP Conjugated - bs-11946R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGRIP1L antibody produced in rabbit - HPA039405 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RPGRIP1L: <B>Cat. No. HPA039405</B>: Immunohistochemical staining of human bronchus shows strong cytoplasmic positivity in respiratory epithelial cells.

Anti-RPGRIP1L antibody produced in goat - SAB2500896 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RPGRIP1L: <B>Cat. No. SAB2500896</B>: (0.3 μg/mL) staining of Human Brain (Cerebellum) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

FTM Antibody - N-terminal region (ARP74187_P050) - ARP74187_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RPGRIP1L-Antibody - AF1944a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1944a (0.3 µg/ml) staining of Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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