Gene Symbol | PRR5L |
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Entrez Gene | 79899 |
Alt Symbol | PROTOR2 |
Species | Human |
Gene Type | protein-coding |
Description | proline rich 5 like |
Other Description | Protein observed with Rictor-2|proline-rich protein 5-like|protor-2 |
Swissprots | Q9H7V4 E9PKY1 Q96H46 A4QN22 Q6MZQ0 |
Accessions | EAW68123 EAW68124 Q6MZQ0 AK024275 BAB14870 AK026283 AK055042 BAG51455 BC008922 AAH08922 BC125122 AAI25123 BX640959 CAE45978 DA269290 DA344861 DA449593 DA458327 DR001466 NM_001160167 NP_001153639 NM_001160168 NP_001153640 NM_001160169 NP_001153641 NM_024841 NP_079117 |
Function | Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton. Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration. {ECO:0000269|PubMed:17461779, ECO:0000269|PubMed:22609986}. |
Protor-2 CRISPR/Cas9 KO Plasmid (h) - sc-413292 from Santa Cruz Biotechnology
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Protor-2 HDR Plasmid (h) - sc-413292-HDR from Santa Cruz Biotechnology
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Protor-2 Double Nickase Plasmid (h) - sc-413292-NIC from Santa Cruz Biotechnology
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Protor-2 Double Nickase Plasmid (h2) - sc-413292-NIC-2 from Santa Cruz Biotechnology
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Protor-2 CRISPR Activation Plasmid (h) - sc-413292-ACT from Santa Cruz Biotechnology
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Protor-2 CRISPR Activation Plasmid (h2) - sc-413292-ACT-2 from Santa Cruz Biotechnology
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Protor-2 Lentiviral Activation Particles (h) - sc-413292-LAC from Santa Cruz Biotechnology
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Protor-2 Lentiviral Activation Particles (h2) - sc-413292-LAC-2 from Santa Cruz Biotechnology
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Protor-2 siRNA (h) - sc-96853 from Santa Cruz Biotechnology
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Protor-2 shRNA Plasmid (h) - sc-96853-SH from Santa Cruz Biotechnology
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Protor-2 shRNA (h) Lentiviral Particles - sc-96853-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17512 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17512 from Sigma-Aldrich
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PRR5L siRNA (Human) - CRJ2653 from Cohesion Biosciences
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shRNA set against Human PRR5 (NM_024841.4) - SHH384120 from Creative biogene
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Human PRR5L siRNA - orb273154 from Biorbyt
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PRR5L shRNA Plasmid (Human) - CHJ2653 from Cohesion Biosciences
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PRR5L miRNA 3'UTR clone - MiUTR4H-TG07083 from Creative biogene
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