Gene Symbol | DLL3 |
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Entrez Gene | 10683 |
Alt Symbol | SCDO1 |
Species | Human |
Gene Type | protein-coding |
Description | delta-like 3 (Drosophila) |
Other Description | delta-like protein 3|delta3|drosophila Delta homolog 3 |
Swissprots | Q9NYJ7 Q8NBS4 E9PFG2 |
Accessions | AAF62542 EAW56905 EAW56906 Q9NYJ7 AA865362 AK075302 BAC11535 AK308460 BC000218 AAH00218 BQ420593 DB035825 DQ891847 ABM82773 DQ895035 ABM85961 NM_016941 NP_058637 NM_203486 NP_982353 |
Function | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Top Pathways | Notch signaling pathway |
Delta-3 CRISPR/Cas9 KO Plasmid (h) - sc-402857 from Santa Cruz Biotechnology
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Delta-3 HDR Plasmid (h) - sc-402857-HDR from Santa Cruz Biotechnology
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Delta-3 Double Nickase Plasmid (h) - sc-402857-NIC from Santa Cruz Biotechnology
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Delta-3 Double Nickase Plasmid (h2) - sc-402857-NIC-2 from Santa Cruz Biotechnology
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Delta-3 CRISPR Activation Plasmid (h) - sc-402857-ACT from Santa Cruz Biotechnology
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Delta-3 CRISPR Activation Plasmid (h2) - sc-402857-ACT-2 from Santa Cruz Biotechnology
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Delta-3 Lentiviral Activation Particles (h) - sc-402857-LAC from Santa Cruz Biotechnology
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Delta-3 Lentiviral Activation Particles (h2) - sc-402857-LAC-2 from Santa Cruz Biotechnology
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Delta-3 siRNA (h) - sc-62206 from Santa Cruz Biotechnology
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Delta-3 shRNA Plasmid (h) - sc-62206-SH from Santa Cruz Biotechnology
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Delta-3 shRNA (h) Lentiviral Particles - sc-62206-V from Santa Cruz Biotechnology
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DLL3 RNAi - H00010683-R02 from Novus Biologicals
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DLL3 RNAi - H00010683-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN7297 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7297 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03843 from Sigma-Aldrich
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DLL3 siRNA (Human) - CRH7286 from Cohesion Biosciences
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DLL3 - MBS8226973 from MyBioSource
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shRNA set against Human DLL3 (NM_016941.3) - SHH278633 from Creative biogene
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DLL3 shRNA Plasmid (Human) - CHH7286 from Cohesion Biosciences
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DLL3 miRNA 3'UTR clone - MiUTR3H-05301 from Creative biogene
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DLL3 miRNA 3'UTR clone - MiUTR3H-05302 from Creative biogene
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