Gene Symbol |
FOXK2
|
Entrez Gene |
3607
|
Alt Symbol |
ILF, ILF-1, ILF1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
forkhead box K2
|
Other Description |
FOXK1|cellular transcription factor ILF-1|forkhead box protein K2|interleukin enhancer binding factor 1|interleukin enhancer-binding factor 1
|
Swissprots |
Q13622 Q01167 A6NEP5 Q13624 Q13623
|
Accessions |
EAW89800 EAW89801 EAW89802 Q01167 AA889932 AK096800 AK098140 AL832570 BC041569 BC169210 U58196 AAB02820 U58197 AAB02821 U58198 AAB02822 XM_011523573 XP_011521875 XR_933935 NM_004514 NP_004505 NM_181430 NM_181431
|
Function |
Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements. {ECO:0000269|PubMed:1339390, ECO:0000269|PubMed:1909027}.
|
Subcellular Location |
Nucleus {ECO:0000305}.
|
Tissue Specificity |
Expressed in both lymphoid and non-lymphoid cells. {ECO:0000269|PubMed:1339390}.
|