Gene Symbol | Arfgap3 |
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Entrez Gene | 66251 |
Alt Symbol | 0610009H19Rik, 1810004P07Rik, 1810035F16Rik, 9130416J18Rik, Arfgap1 |
Species | Mouse |
Gene Type | protein-coding |
Description | ADP-ribosylation factor GTPase activating protein 3 |
Other Description | ADP-ribosylation factor GTPase activating protein 1|ADP-ribosylation factor GTPase-activating protein 3|ARF GAP 3 |
Swissprots | Q9D8S3 Q99KN8 Q544V6 Q8BW06 |
Accessions | EDL04476 Q9D8S3 AK002400 AK007732 BAB25220 AK018680 AK028990 BAC26229 AK075788 BAC35959 AK169107 BAE40889 AK194782 AK215301 BC004081 AAH04081 BC060369 AAH60369 XM_006521253 XP_006521316 XM_006521254 XP_006521317 XM_006521255 XP_006521318 NM_025445 NP_079721 |
Function | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment. {ECO:0000250}. |
Top Pathways | Endocytosis |
ARFGAP1/3 CRISPR/Cas9 KO Plasmid (m) - sc-425913 from Santa Cruz Biotechnology
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ARFGAP1/3 HDR Plasmid (m) - sc-425913-HDR from Santa Cruz Biotechnology
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ARFGAP1/3 Double Nickase Plasmid (m) - sc-425913-NIC from Santa Cruz Biotechnology
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ARFGAP1/3 Double Nickase Plasmid (m2) - sc-425913-NIC-2 from Santa Cruz Biotechnology
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ARFGAP1/3 CRISPR Activation Plasmid (m) - sc-425913-ACT from Santa Cruz Biotechnology
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ARFGAP1/3 CRISPR Activation Plasmid (m2) - sc-425913-ACT-2 from Santa Cruz Biotechnology
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ARFGAP1/3 Lentiviral Activation Particles (m) - sc-425913-LAC from Santa Cruz Biotechnology
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ARFGAP1/3 Lentiviral Activation Particles (m2) - sc-425913-LAC-2 from Santa Cruz Biotechnology
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ARFGAP1/3 siRNA (m) - sc-60201 from Santa Cruz Biotechnology
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ARFGAP1/3 shRNA Plasmid (m) - sc-60201-SH from Santa Cruz Biotechnology
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ARFGAP1/3 shRNA (m) Lentiviral Particles - sc-60201-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU216691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26905 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26905 from Sigma-Aldrich
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ARFGAP3 siRNA (Mouse) - CRM6524 from Cohesion Biosciences
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ARFGAP3 - MBS8200074 from MyBioSource
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shRNA set against Mouse ARFGAP3 (NM_025445.4) - SHH239174 from Creative biogene
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shRNA set against Mouse Arfgap3(NM_025445.4) - SHG068617 from Creative biogene
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Mouse ARFGAP3 siRNA - orb286000 from Biorbyt
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ARFGAP3 shRNA Plasmid (Mouse) - CHM6524 from Cohesion Biosciences
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ARFGAP3 miRNA 3'UTR clone - MiUTR1M-01622 from Creative biogene
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