| Gene Symbol |
NME6
|
| Entrez Gene |
10201
|
| Alt Symbol |
IPIA-ALPHA, NDK 6, NM23-H6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NME/NM23 nucleoside diphosphate kinase 6
|
| Other Description |
NDP kinase 6|inhibitor of p53-induced apoptosis-alpha|non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)|nucleoside diphosphate kinase 6
|
| Swissprots |
Q9BQ63 O75414 B4DGW7 Q96E73 Q53HM5 B4DM99
|
| Accessions |
EAW64861 O75414 AF051941 AAC78463 AK222555 BAD96275 AK294809 BAG57928 AK297364 BAG59811 AK308970 AK309090 AK311152 AL699803 BC001808 AAH01808 BC012828 AAH12828 BE866839 BG284082 BG530435 BQ020663 CA848473 CD701581 CN287719 CT002144 DA398008 DA519225 DA737691 DA912668 DB114903 DQ892283 ABM83209 DQ895483 ABM86409 HY090220 U90449 AAC69439 XM_005264789 XP_005264846 XM_005264790 XP_005264847 XM_005264792 XP_005264849 XM_005264793 XP_005264850 XM_005264794 XP_005264851 XM_011533263 XP_011531565 XR_245088 NM_001308426 NP_001295355 NM_001308427 NP_001295356 NM_001308428 NP_001295357 NM_001308430 NP_001295359 NM_001308431 NP_001295360 NM_001308433 NP_001295362 NM_001308434 NP_001295363 NM_001308435 NP_001295364 NM_005793 NP_005784
|
| Function |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
|
| Tissue Specificity |
Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
|
| Top Pathways |
Purine metabolism, Pyrimidine metabolism
|