Gene Symbol | DGUOK |
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Entrez Gene | 1716 |
Alt Symbol | MTDPS3, dGK |
Species | Human |
Gene Type | protein-coding |
Description | deoxyguanosine kinase |
Other Description | deoxyguanosine kinase, mitochondrial |
Swissprots | Q7L1W9 Q4ZG09 Q16854 Q96BC1 Q16759 P78532 |
Accessions | AAB39858 AAB48932 AAX88910 ADP91894 ADP91895 ADP91896 ADP91897 ADP91898 ADP91899 ADP91900 ADP91901 ADP91902 ADP91903 ADP91904 ADP91905 ADP91906 ADP91907 ADP91908 ADP91909 ADP91910 ADP91911 ADP91912 ADP91913 ADP91914 ADP91915 ADP91916 ADP91917 ADP91918 ADP91919 ADP91920 ADP91921 ADP91922 ADP91923 ADP91924 ADP91925 ADP91926 ADP91927 ADP91928 ADP91929 ADP91930 ADP91931 ADP91932 ADP91933 ADP91934 ADP91935 ADP91936 ADP91937 ADP91938 ADP91939 ADP91940 ADP91941 ADP91942 ADP91943 ADP91944 ADP91945 ADP91946 ADP91947 ADP91948 ADP91949 ADP91950 ADP91951 ADP91952 ADP91953 ADP91954 ADP91955 ADP91956 ADP91957 ADP91958 ADP91959 ADP91960 ADP91961 ADP91962 ADP91963 ADP91964 ADP91965 ADP91966 ADP91967 ADP91968 ADP91969 ADP91970 ADP91971 ADP91972 ADP91973 EAW99704 EAW99706 EAW99709 EAW99710 EAW99711 Q16854 AI201630 AU099795 BC001121 AAH01121 BC015757 AAH15757 BC024019 AAH24019 BG708680 BU580854 U41668 AAC50624 XM_005264173 XP_005264230 XM_005264174 XP_005264231 XM_011532647 XP_011530949 XM_011532648 XP_011530950 XR_244926 NM_080916 NP_550438 NM_080918 NP_550440 NM_001929 NM_080915 NM_080917 |
Function | Required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents. {ECO:0000269|PubMed:8706825}. |
Subcellular Location | Mitochondrion. |
Tissue Specificity | Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues. {ECO:0000269|PubMed:8706825}. |
Top Pathways | Purine metabolism |
DGUOK CRISPR/Cas9 KO Plasmid (h) - sc-407916 from Santa Cruz Biotechnology
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DGUOK HDR Plasmid (h) - sc-407916-HDR from Santa Cruz Biotechnology
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DGUOK Double Nickase Plasmid (h) - sc-407916-NIC from Santa Cruz Biotechnology
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DGUOK Double Nickase Plasmid (h2) - sc-407916-NIC-2 from Santa Cruz Biotechnology
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DGUOK CRISPR Activation Plasmid (h) - sc-407916-ACT from Santa Cruz Biotechnology
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DGUOK CRISPR Activation Plasmid (h2) - sc-407916-ACT-2 from Santa Cruz Biotechnology
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DGUOK Lentiviral Activation Particles (h) - sc-407916-LAC from Santa Cruz Biotechnology
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DGUOK Lentiviral Activation Particles (h2) - sc-407916-LAC-2 from Santa Cruz Biotechnology
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DGUOK siRNA (h) - sc-77139 from Santa Cruz Biotechnology
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DGUOK shRNA Plasmid (h) - sc-77139-SH from Santa Cruz Biotechnology
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DGUOK shRNA (h) Lentiviral Particles - sc-77139-V from Santa Cruz Biotechnology
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Deoxyguanosine kinase RNAi - H00001716-R01V from Novus Biologicals
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Deoxyguanosine kinase RNAi - H00001716-R07 from Novus Biologicals
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Deoxyguanosine kinase RNAi - H00001716-R08 from Novus Biologicals
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Deoxyguanosine kinase RNAi - H00001716-R10 from Novus Biologicals
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Deoxyguanosine kinase RNAi - H00001716-R09 from Novus Biologicals
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Deoxyguanosine kinase RNAi - H00001716-R06 from Novus Biologicals
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MISSION® esiRNA - EHU087751 from Sigma-Aldrich
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MISSION® esiRNA - EHU096571 from Sigma-Aldrich
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MISSION® siRNA - SIHK0604 from Sigma-Aldrich
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MISSION® siRNA - SIHK0603 from Sigma-Aldrich
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MISSION® siRNA - SIHK0602 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7188 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7188 from Sigma-Aldrich
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DGUOK siRNA (Human) - CRH1190 from Cohesion Biosciences
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