| Gene Symbol |
DENND4C
|
| Entrez Gene |
55667
|
| Alt Symbol |
C9orf55, C9orf55B, bA513M16.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DENN/MADD domain containing 4C
|
| Other Description |
DENN domain-containing protein 4C|DENN/MADD domain containing 4A pseudogene
|
| Swissprots |
Q5VZ89 A2A3R1 A2A3R2 A2A3R3 A2A3R9 Q6AI48 Q6ZUB3 Q8NCY7 Q9H6N4 Q9NUT1 Q9NWA5 Q9NWT3
|
| Accessions |
EAW58644 EAW58645 EAW58646 EAW58647 Q5VZ89 AK000627 BAA91294 AK000693 BAA91324 AK001046 BAA91478 AK002020 BAA92039 AK025705 BAB15221 AK125842 BAC86313 AK127734 BAG54561 AK299842 BAH13146 AK302901 BAH13836 AL834521 CAD39177 AW271839 BC144484 BC144485 CN427691 CR627367 CAH10466 DA517991 DV080471 DV080472 HY106197 XM_006716804 XP_006716867 XM_006716805 XP_006716868 XM_006716806 XP_006716869 XM_006716807 XP_006716870 XM_011517959 XP_011516261 NM_017925 NP_060395 NR_073201
|
| Function |
Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin. {ECO:0000269|PubMed:20937701}.
|
| Subcellular Location |
Cytoplasmic vesicle membrane. Cell membrane. Cytoplasm, cytosol. Note=Associates with SLC2A4/GLUT4 storage vesicles.
|