Gene Symbol |
PRDX3
|
Entrez Gene |
10935
|
Alt Symbol |
AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
peroxiredoxin 3
|
Other Description |
antioxidant protein 1|peroxiredoxin III|peroxiredoxin-3|protein MER5 homolog|thioredoxin-dependent peroxide reductase, mitochondrial
|
Swissprots |
Q96HK4 D3DRC9 Q0D2H1 Q5T5V2 P35690 Q13776 E9PH29 B2R7Z0 P30048
|
Accessions |
ABB84468 EAW49396 EAW49397 EAW49398 EAW49399 P30048 AF118073 AAF22017 AK130897 AK222659 BAD96379 AK313169 BAG35987 AV718278 AV737791 AV761690 BC002685 AAH02685 BC007062 AAH07062 BC008435 AAH08435 BC009601 AAH09601 BC021691 AAH21691 BC022373 AAH22373 BC059169 AAH59169 BC111397 AAI11398 BF209381 BG115645 BG282768 BM144742 BT020007 AAV38810 BX382389 CD687044 CR450344 CAG29340 D49396 BAA08389 EF036492 ABO65078 HY082255 HY173455 X85129 CAA59443 NM_001302272 NP_001289201 NM_006793 NP_006784 NR_126102 NR_126103 NR_126105 NR_126106 NM_014098
|
Function |
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. {ECO:0000269|PubMed:12492477}.
|
Subcellular Location |
Mitochondrion.
|