| Gene Symbol | CNR1 |
|---|---|
| Entrez Gene | 1268 |
| Alt Symbol | CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR |
| Species | Human |
| Gene Type | protein-coding |
| Description | cannabinoid receptor 1 (brain) |
| Other Description | cannabinoid receptor 1|central cannabinoid receptor |
| Swissprots | Q13949 E1P512 Q5JVL5 B2R9T4 Q5UB37 P21554 Q9UNN0 Q495Z0 Q4PLI4 Q4VBM6 |
| Accessions | AAB18200 AAG37765 AAO67710 AGS49222 EAW48574 EAW48575 EAW48576 P21554 AF107262 AAD34320 AK313908 BAG36631 AY766182 AAV35030 AY995204 AAY21179 BC074811 AAH74811 BC074812 AAH74812 BC095513 AAH95513 BC100968 AAI00969 BC100969 AAI00970 BC100970 AAI00971 BC100971 AAI00972 BM682178 BX538191 DA128033 DA239984 DA768458 DA793373 DA799263 DQ067455 AAY68486 KC292264 AGW25490 X54937 CAA38699 X81120 CAA57018 X81121 CAA57019 XM_005248650 XP_005248707 XM_006715330 XP_006715393 XM_011535424 XP_011533726 XM_011535425 XP_011533727 XM_011535426 XP_011533728 XM_011535427 XP_011533729 XM_011535428 XP_011533730 NM_001160226 NP_001153698 NM_001160258 NP_001153730 NM_001160259 NP_001153731 NM_016083 NP_057167 NM_033181 NP_149421 NM_001160260 |
| Function | Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. {ECO:0000269|PubMed:15620723}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15620723}. |
| Top Pathways | Retrograde endocannabinoid signaling, Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
Mouse Cannabinoid R1/CB1/CNR1 (NP_031752) VersaClone cDNA - RDC0222 from R&D Systems
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Human Cannabinoid R1/CB1/CNR1 (NP_057167) VersaClone cDNA - RDC0109 from R&D Systems
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Rat Cannabinoid R1/CB1/CNR1 (NP_036916) VersaClone cDNA - RDC0757 from R&D Systems
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Human CNR1 cDNA clone(NM_033181.3) - CDFG006682 from Creative Biomart
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Human CNR1 cDNA clone(NM_001160226.1) - CDFH003968 from Creative Biomart
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Human CNR1 cDNA clone(NM_001160258.1) - CDFH003969 from Creative Biomart
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Human CNR1 cDNA clone(NM_001160259.1) - CDFH003971 from Creative Biomart
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Human CNR1 ORF Clone(NM_033181.3) - CDCR313551 from Creative Biomart
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Human CNR1 ORF Clone(NM_033181.3) - CDCR313553 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160226.1) - CDCR353745 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160226.1) - CDCR353746 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160258.1) - CDCR353912 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160259.1) - CDCR353913 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160259.1) - CDCR353914 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160258.1) - CDCR353919 from Creative Biomart
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Human CNR1 ORF Clone(NM_001160226.1) - CDCR353745 from Creative biogene
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Human CNR1 ORF Clone(NM_001160258.1) - CDCR353912 from Creative biogene
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Human CNR1 ORF Clone(NM_001160259.1) - CDCR353913 from Creative biogene
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Human CNR1 ORF clone (NM_033181.3) - CDCR048902 from Creative biogene
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Human CNR1 ORF clone (NM_016083.4) - CDCR048904 from Creative biogene
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Human CNR1 cDNA Clone(NM_033181.3) - CDFG006682 from Creative biogene
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Human CNR1 cDNA Clone(NM_001160226.1) - CDFH003968 from Creative biogene
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Human CNR1 cDNA Clone(NM_001160258.1) - CDFH003969 from Creative biogene
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Human CNR1 cDNA Clone(NM_001160259.1) - CDFH003971 from Creative biogene
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