Gene Symbol | LRFN2 |
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Entrez Gene | 57497 |
Alt Symbol | FIGLER2, KIAA1246, SALM1 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat and fibronectin type III domain containing 2 |
Other Description | fibronectin type III, immunoglobulin and leucine rich repeat domains 2|leucine-rich repeat and fibronectin type-III domain-containing protein 2|synaptic adhesion-like molecule 1 |
Swissprots | Q5SYP9 Q9ULH4 A5PKU3 |
Accessions | EAX04006 Q9ULH4 AB033072 BAA86560 AK291474 BAF84163 BC142616 AAI42617 DA779371 HG499215 XM_011514759 XP_011513061 XM_011514760 XP_011513062 XM_011514761 XP_011513063 XM_011514762 XP_011513064 XM_011514763 XP_011513065 XR_926281 XR_926282 XR_926283 NM_020737 NP_065788 |
Function | Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. |
LRFN2 CRISPR/Cas9 KO Plasmid (h) - sc-410606 from Santa Cruz Biotechnology
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LRFN2 HDR Plasmid (h) - sc-410606-HDR from Santa Cruz Biotechnology
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LRFN2 Double Nickase Plasmid (h) - sc-410606-NIC from Santa Cruz Biotechnology
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LRFN2 Double Nickase Plasmid (h2) - sc-410606-NIC-2 from Santa Cruz Biotechnology
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LRFN2 CRISPR Activation Plasmid (h) - sc-410606-ACT from Santa Cruz Biotechnology
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LRFN2 CRISPR Activation Plasmid (h2) - sc-410606-ACT-2 from Santa Cruz Biotechnology
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LRFN2 Lentiviral Activation Particles (h) - sc-410606-LAC from Santa Cruz Biotechnology
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LRFN2 Lentiviral Activation Particles (h2) - sc-410606-LAC-2 from Santa Cruz Biotechnology
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LRFN2 siRNA (h) - sc-95053 from Santa Cruz Biotechnology
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LRFN2 shRNA Plasmid (h) - sc-95053-SH from Santa Cruz Biotechnology
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LRFN2 shRNA (h) Lentiviral Particles - sc-95053-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU038441 from Sigma-Aldrich
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MISSION® esiRNA - EHU136941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12674 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12674 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02684 from Sigma-Aldrich
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LRFN2 siRNA (Human) - CRJ1486 from Cohesion Biosciences
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shRNA set against Human LRFN2 (NM_020737.1) - SHH333787 from Creative biogene
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LRFN2 shRNA Plasmid (Human) - CHJ1486 from Cohesion Biosciences
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LRFN2 miRNA 3'UTR clone - MiUTR1H-05890 from Creative biogene
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