Gene Symbol | SCARB2 |
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Entrez Gene | 950 |
Alt Symbol | AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII |
Species | Human |
Gene Type | protein-coding |
Description | scavenger receptor class B, member 2 |
Other Description | 85 kDa lysosomal membrane sialoglycoprotein|85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)|CD36 antigen-like 2|LIMP II|lysosome membrane protein 2|lysosome membrane protein II |
Swissprots | B4DKD8 E7EM68 Q14108 Q53Y63 |
Accessions | CCO13808 EAX05779 EAX05780 EAX05781 Q14108 AK022432 AK056001 AK296519 BAG59150 AK313016 BAG35851 BC021892 AAH21892 BC035111 BQ924546 BT006939 AAP35585 BT007661 AAP36329 CA395147 D12676 BAA02177 DQ893535 ABM84461 DQ893757 ABM84683 NM_001204255 NP_001191184 NM_005506 NP_005497 |
Function | Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. {ECO:0000269|PubMed:18022370}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370, ECO:0000269|PubMed:7509809}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370, ECO:0000269|PubMed:7509809}. |
Top Pathways | Lysosome |
LIMP II CRISPR/Cas9 KO Plasmid (h) - sc-402532 from Santa Cruz Biotechnology
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LIMP II HDR Plasmid (h) - sc-402532-HDR from Santa Cruz Biotechnology
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LIMP II Double Nickase Plasmid (h) - sc-402532-NIC from Santa Cruz Biotechnology
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LIMP II Double Nickase Plasmid (h2) - sc-402532-NIC-2 from Santa Cruz Biotechnology
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LIMP II CRISPR Activation Plasmid (h) - sc-402532-ACT from Santa Cruz Biotechnology
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LIMP II CRISPR Activation Plasmid (h2) - sc-402532-ACT-2 from Santa Cruz Biotechnology
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LIMP II Lentiviral Activation Particles (h) - sc-402532-LAC from Santa Cruz Biotechnology
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LIMP II Lentiviral Activation Particles (h2) - sc-402532-LAC-2 from Santa Cruz Biotechnology
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LIMP II siRNA (h) - sc-41546 from Santa Cruz Biotechnology
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LIMP II shRNA Plasmid (h) - sc-41546-SH from Santa Cruz Biotechnology
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LIMP II shRNA (h) Lentiviral Particles - sc-41546-V from Santa Cruz Biotechnology
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LIMPII/SR-B2 RNAi - H00000950-R02 from Novus Biologicals
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MISSION® esiRNA - EHU040301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18894 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18894 from Sigma-Aldrich
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SCARB2 siRNA (Human) - CRH0672 from Cohesion Biosciences
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SCARB2 - MBS8227617 from MyBioSource
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shRNA set against Human SCARB2 (NM_005506.3) - SHH402420 from Creative biogene
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SCARB2 shRNA Plasmid (Human) - CHH0672 from Cohesion Biosciences
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