Gene Symbol | UQCRC1 |
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Entrez Gene | 7384 |
Alt Symbol | D3S3191, QCR1, UQCR1 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase core protein I |
Other Description | complex III subunit 1|core protein I|cytochrome b-c1 complex subunit 1, mitochondrial|ubiquinol-cytochrome-c reductase complex core protein 1 |
Swissprots | B2R7R8 Q96DD2 P31930 |
Accessions | EAW64898 P31930 AA284910 AK129903 AK300694 BAG62377 AK302840 BAG64031 AK313090 BAG35915 BC009586 AAH09586 D26485 BAA05495 L16842 AAA20046 NM_003365 NP_003356 |
Function | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
UQCRC1 CRISPR/Cas9 KO Plasmid (h) - sc-404435 from Santa Cruz Biotechnology
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UQCRC1 HDR Plasmid (h) - sc-404435-HDR from Santa Cruz Biotechnology
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UQCRC1 Double Nickase Plasmid (h) - sc-404435-NIC from Santa Cruz Biotechnology
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UQCRC1 Double Nickase Plasmid (h2) - sc-404435-NIC-2 from Santa Cruz Biotechnology
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UQCRC1 CRISPR Activation Plasmid (h) - sc-404435-ACT from Santa Cruz Biotechnology
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UQCRC1 CRISPR Activation Plasmid (h2) - sc-404435-ACT-2 from Santa Cruz Biotechnology
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UQCRC1 Lentiviral Activation Particles (h) - sc-404435-LAC from Santa Cruz Biotechnology
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UQCRC1 Lentiviral Activation Particles (h2) - sc-404435-LAC-2 from Santa Cruz Biotechnology
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UQCRC1 siRNA (h) - sc-72154 from Santa Cruz Biotechnology
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UQCRC1 shRNA Plasmid (h) - sc-72154-SH from Santa Cruz Biotechnology
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UQCRC1 shRNA (h) Lentiviral Particles - sc-72154-V from Santa Cruz Biotechnology
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UQCRC1 RNAi - H00007384-R01 from Novus Biologicals
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MISSION® esiRNA - EHU024651 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22533 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22533 from Sigma-Aldrich
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UQCRC1 siRNA (Human) - CRH5051 from Cohesion Biosciences
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UQCRC1 - MBS8228919 from MyBioSource
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shRNA set against Human UQCRC1 (NM_003365.2) - SHH440936 from Creative biogene
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shRNA set against Human UQCRC1(NM_003365.2) - SHL116316 from Creative biogene
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Human UQCRC1 siRNA - orb265553 from Biorbyt
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UQCRC1 shRNA Plasmid (Human) - CHH5051 from Cohesion Biosciences
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UQCRC1 miRNA 3'UTR clone - MiUTR1H-11031 from Creative biogene
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