| Gene Symbol |
CSAG3
|
| Entrez Gene |
389903
|
| Alt Symbol |
CSAG3A, CT24.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CSAG family, member 3
|
| Other Description |
CSAG family, member 3A|cancer/testis antigen 24.2|chondrosarcoma-associated gene 2/3 protein|taxol resistance associated gene 3|taxol-resistant-associated gene 3 protein
|
| Swissprots |
Q96IU8 O75605 Q0VDC3 Q9Y5P2
|
| Accessions |
EAW99427 EAW99428 Q9Y5P2 AF080246 AAC29487 AF136715 AAD37859 AF268420 AJ844639 CAH59758 BC007228 AAH07228 BC119734 AAI19735 BC119735 AAI19736 NM_203311 NM_001129826 NP_001123298 NM_001129828 NP_001123300 NR_130638
|
| Function |
Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.
|
| Tissue Specificity |
Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435TR and the doxorubicin-resistant multiple myelanoma lines RPMI-8226/Dox40 and RPMI-8226/MDR10V.
|