ACACB

Gene Symbol ACACB
Entrez Gene 32
Alt Symbol ACC2, ACCB, HACC275
Species Human
Gene Type protein-coding
Description acetyl-CoA carboxylase beta
Other Description ACC-beta|acetyl-CoA carboxylase 2|acetyl-Coenzyme A carboxylase beta
Swissprots A6NK36 Q6TY48 Q16852 O00763 Q6KE89 Q1HEC1 Q6KE87
Accessions EAW97852 EAW97853 EAW97854 EAW97855 O00763 AB209110 BAD92347 AJ575431 CAE01470 AJ575592 CAE01471 AK302469 BAG63759 AK302502 BAG63782 AK307466 AY382667 AAR37018 AY701053 BC009753 BC028417 AAH28417 BC172264 AAI72264 BC172569 AAI72569 CB269093 CB269579 DB567934 DQ493870 ABF48723 HG505159 R99037 U34591 AAC50571 U89344 AAB58382 XM_005253876 XP_005253933 XM_006719365 XP_006719428 XM_006719367 XP_006719430 XM_011538259 XP_011536561 XM_011538260 XP_011536562 XM_011538261 XP_011536563 XM_011538262 XP_011536564 XM_011538263 XP_011536565 XM_011538264 XP_011536566 XM_011538265 XP_011536567 XR_944530 XR_944531 XR_944532 XR_944533 NM_001093 NP_001084
Function Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl- CoA-dependent inhibition of carnitine palmitoyltransferase 1 (By similarity). {ECO:0000250|UniProtKB:E9Q4Z2, ECO:0000269|PubMed:20952656}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:10677481}. Nucleus {ECO:0000269|PubMed:10677481}. Endomembrane system. Note=May associate with membranes.
Tissue Specificity Widely expressed with highest levels in heart, skeletal muscle, liver, adipose tissue, mammary gland, adrenal gland and colon (PubMed:9099716). Isoform 3 is expressed in skeletal muscle, adipose tissue and liver (at protein level) (PubMed:19190759). Isoform 3 is detected at high levels in adipose tissue with lower levels in heart, liver, skeletal muscle and testis (PubMed:19190759). {ECO:0000269|PubMed:19190759, ECO:0000269|PubMed:9099716}.
Top Pathways Glucagon signaling pathway, AMPK signaling pathway, Adipocytokine signaling pathway, Insulin signaling pathway, Pyruvate metabolism

Acetyl-CoA carboxylase 2 (ACACB), Human, ELISA Kit - E01A1170 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Acetyl CoA carboxylase 2 (ACACB), ELISA Kit - MBS7215485 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7229963 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7239707 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7209758 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7236667 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7229543 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7234941 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7253133 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7211428 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7226818 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7220677 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS7213562 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

acetyl-Coenzyme A carboxylase beta, ELISA Kit - MBS2602872 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ACCB ELISA Kit - E000233 from Biobool

Category ELISA Kit

Human ACACB ELISA Kit - E000251 from Biobool

Category ELISA Kit
Sensitivity < 28.125pg/ml

Human ACACB ELISA Kit - E074312 from Biobool

Category ELISA Kit

Acetyl-CoA carboxylase 2 (ACACB), ELISA Kit - MBS2610451 from MyBioSource

Category ELISA Kit
Prices $300.00, $475.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2603127 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2606293 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2603667 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2605453 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2605275 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2607434 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acetyl-CoA carboxylase 2, ELISA Kit - MBS2603614 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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