Gene Symbol | TLX1 |
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Entrez Gene | 3195 |
Alt Symbol | HOX11, TCL3 |
Species | Human |
Gene Type | protein-coding |
Description | T-cell leukemia homeobox 1 |
Other Description | T-cell leukemia homeobox protein 1|T-cell leukemia/lymphoma protein 3|homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch)|homeobox protein Hox-11|proto-oncogene TCL-3 |
Swissprots | O75699 Q9UD59 P31314 Q9HCA0 Q5VXP2 A1L4G3 |
Accessions | AAG10096 CAA08834 EAW49778 P31314 BC130530 AAI30531 BF514683 M62626 AAA36719 M75952 AAA58662 S38742 AAB19293 XM_011539744 XP_011538046 XM_011539745 XP_011538047 NM_001195517 NP_001182446 NM_005521 NP_005512 |
Function | Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Transcriptional misregulation in cancer |
Hox11 CRISPR/Cas9 KO Plasmid (h) - sc-404662 from Santa Cruz Biotechnology
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Hox11 HDR Plasmid (h) - sc-404662-HDR from Santa Cruz Biotechnology
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Hox11 Double Nickase Plasmid (h) - sc-404662-NIC from Santa Cruz Biotechnology
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Hox11 Double Nickase Plasmid (h2) - sc-404662-NIC-2 from Santa Cruz Biotechnology
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Hox11 CRISPR Activation Plasmid (h) - sc-404662-ACT from Santa Cruz Biotechnology
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Hox11 CRISPR Activation Plasmid (h2) - sc-404662-ACT-2 from Santa Cruz Biotechnology
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Hox11 Lentiviral Activation Particles (h) - sc-404662-LAC from Santa Cruz Biotechnology
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Hox11 Lentiviral Activation Particles (h2) - sc-404662-LAC-2 from Santa Cruz Biotechnology
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Hox11 siRNA (h) - sc-38700 from Santa Cruz Biotechnology
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Hox11 shRNA Plasmid (h) - sc-38700-SH from Santa Cruz Biotechnology
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Hox11 shRNA (h) Lentiviral Particles - sc-38700-V from Santa Cruz Biotechnology
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HOX11 RNAi - H00003195-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21407 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21407 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07080 from Sigma-Aldrich
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TLX1 siRNA (Human) - CRH2183 from Cohesion Biosciences
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TLX1 - MBS8216671 from MyBioSource
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shRNA set against Human Tlx1 (NM_005521.3) - SHH428056 from Creative biogene
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Human TLX1 siRNA - orb262685 from Biorbyt
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TLX1 shRNA Plasmid (Human) - CHH2183 from Cohesion Biosciences
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TLX1 miRNA 3'UTR clone - MiUTR3H-02172 from Creative biogene
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