| Gene Symbol |
KRTAP10-4
|
| Entrez Gene |
386672
|
| Alt Symbol |
KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 10-4
|
| Other Description |
high sulfur keratin-associated protein 10.4|keratin-associated protein 10-4|keratin-associated protein 18.4
|
| Swissprots |
P60372 Q08AS0
|
| Accessions |
EAX09416 P60372 AB076351 BAD01538 AJ566382 BC125048 AAI25049 BC125049 AAI25050 NM_198687 NP_941960
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Restricted to hair root, not detected in any other tissues.
|