| Gene Symbol |
MFI2
|
| Entrez Gene |
4241
|
| Alt Symbol |
CD228, MAP97, MTF1, MTf
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
|
| Other Description |
melanoma-associated antigen p97|melanotransferrin|membrane-bound transferrin-like protein
|
| Swissprots |
Q9BQE2 P08582
|
| Accessions |
EAW53616 EAW53617 P08582 A00127 CAA00012 AA442552 AK096182 AU099352 AW083943 BC001875 AAH01875 BC002623 AAH02623 BC007550 AAH07550 BC032752 BC034933 BC053510 BC068085 BC071910 AAH71910 BC082761 BC093920 AAH93920 BC111947 AAI11948 BC143257 BC152832 AAI52833 BQ332373 BT007377 AAP36041 K03200 M12154 AAA59992 XM_006713643 XP_006713706 XM_006713644 XP_006713707 XM_011512850 XP_011511152 XM_011512851 XP_011511153 NM_005929 NP_005920 NM_033316 NP_201573
|
| Function |
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. {ECO:0000269|PubMed:7556058}.
|
| Subcellular Location |
Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor.
|
| Tissue Specificity |
Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.
|