Gene Symbol | PRDM9 |
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Entrez Gene | 56979 |
Alt Symbol | MEISETZ, MSBP3, PFM6, PRMD9, ZNF899 |
Species | Human |
Gene Type | protein-coding |
Description | PR domain containing 9 |
Other Description | PR domain zinc finger protein 9|histone-lysine N-methyltransferase PRDM9|minisatellite binding protein 3 (115kD)|minisatellite binding protein 3, 115kDa |
Swissprots | Q9NQV7 Q27Q50 B4DX22 |
Accessions | ADA68123 ADA68124 ADA68125 ADA68126 ADA68127 ADA68128 ADA68129 ADA68130 ADA68131 ADA68132 ADA68133 ADA68134 ADA68135 ADA68136 ADA68137 ADA68138 ADA68139 ADA68140 ADA68141 ADA68142 ADA68143 ADA68144 ADA68145 ADA68146 ADA68147 ADA68148 ADA68149 ADA68150 ADA68151 ADA68152 ADA68153 ADA68154 ADA68155 ADA68156 ADA68157 ADA68158 ADA68159 ADA68160 ADA68161 ADA68162 ADA68163 ADA68164 ADA68165 ADA68166 ADA68167 ADA68168 ADA68169 ADA68170 ADA68171 ADA68172 ADA71141 ADA71142 ADA71144 ADA81880 ADA81881 ADA81882 ADA81883 ADA81884 ADA81885 ADK09877 ADK09878 ADK09879 ADK09880 ADK09881 ADK09882 ADK09883 ADK09884 ADK09885 ADK09886 ADK09887 ADK09888 ADK09889 ADK09890 ADK09891 ADK09892 ADK09893 ADK09895 ADK09896 ADK09897 ADK09898 ADK09899 ADK09900 AFN20613 AFN80344 AFN80345 AFN80346 AFN80347 AFN80348 AFN80349 AFN80350 AGZ95141 AGZ95142 AGZ95143 AGZ95144 AGZ95145 AGZ95146 AGZ95147 AGZ95148 EAX10738 EAX10739 EAX10740 Q9NQV7 AF275816 AAF87242 AK301776 BAG63234 DQ388610 ABD47939 GU216222 ADA71145 GU216223 ADA71146 GU216227 ADA71147 GU216228 ADA71148 NM_020227 NP_064612 |
Function | Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. |
PRDM9 CRISPR/Cas9 KO Plasmid (h) - sc-412740 from Santa Cruz Biotechnology
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PRDM9 HDR Plasmid (h) - sc-412740-HDR from Santa Cruz Biotechnology
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PRDM9 Double Nickase Plasmid (h) - sc-412740-NIC from Santa Cruz Biotechnology
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PRDM9 Double Nickase Plasmid (h2) - sc-412740-NIC-2 from Santa Cruz Biotechnology
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PRDM9 CRISPR Activation Plasmid (h) - sc-412740-ACT from Santa Cruz Biotechnology
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PRDM9 CRISPR Activation Plasmid (h2) - sc-412740-ACT-2 from Santa Cruz Biotechnology
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PRDM9 Lentiviral Activation Particles (h) - sc-412740-LAC from Santa Cruz Biotechnology
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PRDM9 Lentiviral Activation Particles (h2) - sc-412740-LAC-2 from Santa Cruz Biotechnology
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PRDM9 siRNA (h) - sc-92022 from Santa Cruz Biotechnology
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PRDM9 shRNA Plasmid (h) - sc-92022-SH from Santa Cruz Biotechnology
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PRDM9 shRNA (h) Lentiviral Particles - sc-92022-V from Santa Cruz Biotechnology
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PRDM9 RNAi - H00056979-R01 from Novus Biologicals
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MISSION® esiRNA - EHU113641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17381 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07382 from Sigma-Aldrich
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PRDM9 siRNA (Human) - CRJ1266 from Cohesion Biosciences
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shRNA set against Human Prdm9 (NM_020227.2) - SHH382288 from Creative biogene
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PRDM9 shRNA Plasmid (Human) - CHJ1266 from Cohesion Biosciences
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PRDM9 miRNA 3'UTR clone - MiUTR1H-08233 from Creative biogene
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