Gene Symbol | HIST3H2A |
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Entrez Gene | 92815 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 3, H2a |
Other Description | histone 3, H2a|histone H2A type 3 |
Swissprots | B2R4S4 Q7L7L0 |
Accessions | AAN59960 EAW69878 Q7L7L0 AK311930 BAG34871 BC001193 BC082269 NM_033445 NP_254280 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Histone cluster 3 H2A CRISPR/Cas9 KO Plasmid (h) - sc-413957 from Santa Cruz Biotechnology
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Histone cluster 3 H2A HDR Plasmid (h) - sc-413957-HDR from Santa Cruz Biotechnology
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Histone cluster 3 H2A Double Nickase Plasmid (h) - sc-413957-NIC from Santa Cruz Biotechnology
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Histone cluster 3 H2A Double Nickase Plasmid (h2) - sc-413957-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 3 H2A CRISPR Activation Plasmid (h) - sc-413957-ACT from Santa Cruz Biotechnology
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Histone cluster 3 H2A CRISPR Activation Plasmid (h2) - sc-413957-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 3 H2A Lentiviral Activation Particles (h) - sc-413957-LAC from Santa Cruz Biotechnology
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Histone cluster 3 H2A Lentiviral Activation Particles (h2) - sc-413957-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 3 H2A siRNA (h) - sc-105517 from Santa Cruz Biotechnology
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Histone cluster 3 H2A shRNA Plasmid (h) - sc-105517-SH from Santa Cruz Biotechnology
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Histone cluster 3 H2A shRNA (h) Lentiviral Particles - sc-105517-V from Santa Cruz Biotechnology
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Histone 3 H2a RNAi - H00092815-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN10117 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10117 from Sigma-Aldrich
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HIST3H2A siRNA (Human) - CRJ4169 from Cohesion Biosciences
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HIST3H2A - MBS8225156 from MyBioSource
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shRNA set against Human HIST3H2A (NM_033445.2) - SHH312985 from Creative biogene
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shRNA set against Human HIST3H2A(NM_033445.2) - SHH123851 from Creative biogene
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HIST3H2A shRNA Plasmid (Human) - CHJ4169 from Cohesion Biosciences
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HIST3H2A miRNA 3'UTR clone - MiUTR1H-04571 from Creative biogene
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