| Gene Symbol |
LIPG
|
| Entrez Gene |
9388
|
| Alt Symbol |
EDL, EL, PRO719
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lipase, endothelial
|
| Other Description |
endothelial cell-derived lipase|endothelial lipase|lipoprotein lipase H
|
| Swissprots |
Q6P9C8 Q9Y5X9 B0LPG6 Q6UW82
|
| Accessions |
ABY87545 EAW62947 EAW62948 EAW62949 Q9Y5X9 AF118767 AAD30434 AI861822 AK124636 AK125344 AK291799 BAF84488 AK300333 BAG62080 AK315252 BAG37674 AY358928 AAQ89287 BC060825 AAH60825 DC381775 HQ448045 ADQ32526 XM_005258390 XP_005258447 XM_011526265 XP_011524567 XM_011526266 XP_011524568 XM_011526267 XP_011524569 NM_001308006 NP_001294935 NM_006033 NP_006024
|
| Function |
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle.
|
| Top Pathways |
Glycerolipid metabolism
|
