CACNB2

Gene Symbol	CACNB2
Entrez Gene	783
Alt Symbol	CACNLB2, CAVB2, MYSB
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, beta 2 subunit
Other Description	CAB2|calcium channel voltage-dependent subunit beta 2|lambert-Eaton myasthenic syndrome antigen B|myasthenic (Lambert-Eaton) syndrome antigen B|voltage-dependent L-type calcium channel subunit beta-2
Swissprots	Q6TME3 Q9Y341 Q5VWV6 A6PVM8 A6PVM5 Q96NZ4 A6PVM7 Q9Y340 Q6TME1 O00304 Q6TME2 Q96NZ3 Q5QJA0 Q5QJ99 Q8WX81 Q5VVG9 Q96NZ5 Q5VVH0 Q9BWU2 Q08289 Q9HD32
Accessions	AAB27916 AAK16994 EAW86193 EAW86194 EAW86195 EAW86196 EAW86197 Q08289 AB208917 BAD92154 AF137376 AAD33729 AF137377 AAD33730 AF285239 AAG01473 AF423189 AAL16948 AF423190 AAL16949 AF423191 AAL16950 AF423192 AAL16951 AF465485 AAL73495 AK021994 AK022426 AK128769 AK293837 BAH11608 AK293937 BAH11631 AK295113 BAH11979 AK296471 BAH12366 AK299873 BAH13158 AK307526 AK307800 AK310943 AK311694 AL119895 AL599294 AL600557 AY393858 AAQ97606 AY393859 AAQ97607 AY393860 AAQ97608 AY393861 AAQ97609 AY393862 AAQ97610 AY393863 AAQ97611 AY675091 AAV49501 AY675092 AAV49502 BC136409 AAI36410 BM312516 DB235418 DC307859 DC352526 S60415 AAB51370 U95019 AAB53332 XM_005252588 XP_005252645 XM_005252591 XP_005252648 XM_006717502 XP_006717565 XM_011519659 XP_011517961 XM_011519660 XP_011517962 NM_000724 NP_000715 NM_001167945 NP_001161417 NM_201570 NP_963864 NM_201571 NP_963865 NM_201572 NP_963866 NM_201590 NP_963884 NM_201593 NP_963887 NM_201596 NP_963890 NM_201597 NP_963891
Function	The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Subcellular Location	Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Tissue Specificity	Expressed in all tissues.
Top Pathways	MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

L-type Ca ++ CP β2 (F-29) - sc-81890 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-CACNB2 antibody - ab54920 from Abcam Prices $392.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-CACNB2 antibody - ab49131 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CACNB2 antibody - ab81159 from Abcam Host Rabbit Clonality Polyclonal

Anti-CACNB2 antibody [S8b-1] - ab93606 from Abcam Prices $387.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa565-579) - LS-C154917 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-CACNB2 Antibody (aa232-261) - LS-C168262 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 390) - LS-C227707 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 594) - LS-C227706 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa259-308) - LS-C201310 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 633) - LS-C227708 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa251-300) - LS-C169524 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 655) - LS-C227709 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 700) - LS-C227710 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Atto 680) - LS-C227711 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, PerCP) - LS-C227712 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, RPE) - LS-C227713 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, SA) - LS-C227714 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, AP) - LS-C229876 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, APC) - LS-C229875 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, FITC) - LS-C229878 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, Biotin) - LS-C229877 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

Anti-CACNB2 Antibody (clone 6C1) - LS-C196801 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6C1

Anti-CACNB2 Antibody (aa231-261) - LS-C319975 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-CACNB2 Antibody (aa189-205, clone S8b-1, PE, Atto 594) - LS-C229882 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S8b-1

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