Gene Symbol | SPCS2 |
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Entrez Gene | 9789 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | signal peptidase complex subunit 2 homolog (S. cerevisiae) |
Other Description | SPase 25 kDa subunit|microsomal signal peptidase 25 kDa subunit|signal peptidase 25kDa subunit|signal peptidase complex subunit 2 |
Swissprots | Q6IRX0 Q6FG65 Q6P1P4 Q96HU9 Q641R4 Q15507 Q15005 Q3KQT0 |
Accessions | CAH05355 CAH05372 EAW74952 Q15005 AA921960 AK293128 BAG56680 BC008063 AAH08063 BC064957 AAH64957 BC067821 BC070276 AAH70276 BC082231 AAH82231 BC106066 AAI06067 BP338843 CR542233 CAG47029 CR542243 CAG47039 D14658 BAA03492 HQ448126 ADQ32607 NM_014752 NP_055567 |
Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Protein export |
SPCS2 CRISPR/Cas9 KO Plasmid (h) - sc-411344 from Santa Cruz Biotechnology
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SPCS2 HDR Plasmid (h) - sc-411344-HDR from Santa Cruz Biotechnology
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SPCS2 Double Nickase Plasmid (h) - sc-411344-NIC from Santa Cruz Biotechnology
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SPCS2 Double Nickase Plasmid (h2) - sc-411344-NIC-2 from Santa Cruz Biotechnology
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SPCS2 CRISPR Activation Plasmid (h) - sc-411344-ACT from Santa Cruz Biotechnology
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SPCS2 CRISPR Activation Plasmid (h2) - sc-411344-ACT-2 from Santa Cruz Biotechnology
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SPCS2 Lentiviral Activation Particles (h) - sc-411344-LAC from Santa Cruz Biotechnology
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SPCS2 Lentiviral Activation Particles (h2) - sc-411344-LAC-2 from Santa Cruz Biotechnology
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SPCS2 siRNA (h) - sc-97020 from Santa Cruz Biotechnology
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SPCS2 shRNA Plasmid (h) - sc-97020-SH from Santa Cruz Biotechnology
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SPCS2 shRNA (h) Lentiviral Particles - sc-97020-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU106861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20438 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20438 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05931 from Sigma-Aldrich
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SPCS2 siRNA (Human) - CRH6551 from Cohesion Biosciences
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SPCS2 - MBS8219678 from MyBioSource
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shRNA set against Human SPCS2 (NM_014752.2) - SHH416324 from Creative biogene
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shRNA set against Human SPCS2(NM_014752.2) - SHL027560 from Creative biogene
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Human SPCS2 siRNA - orb267053 from Biorbyt
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SPCS2 shRNA Plasmid (Human) - CHH6551 from Cohesion Biosciences
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SPCS2 miRNA 3'UTR clone - MiUTR1H-09827 from Creative biogene
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