Gene Symbol | TCL1B |
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Entrez Gene | 9623 |
Alt Symbol | SYN-1, TML1 |
Species | Human |
Gene Type | protein-coding |
Description | T-cell leukemia/lymphoma 1B |
Other Description | T-cell leukemia/lymphoma protein 1B|T-cell lymphoma/leukemia 1B|TCL1/ MTCP1-like 1|oncogene TCL-1B|syncytiotrophoblast-specific protein |
Swissprots | Q9UBQ4 Q6IAR7 O95988 A6NEK7 |
Accessions | AAD16996 BAA82476 EAW81619 EAW81620 O95988 AB018563 BAA76712 AF110466 AAD16997 AF137027 AAD30130 AI250350 BC041616 AAH41616 BC051000 AAH51000 BQ058954 CR457087 CAG33368 NM_199206 NM_004918 NP_004909 |
Function | Enhances the phosphorylation and activation of AKT1 and AKT2. {ECO:0000269|PubMed:10983986}. |
Tissue Specificity | Expressed in a variety of tissues including placenta and testis. {ECO:0000269|PubMed:10077617, ECO:0000269|PubMed:10344735}. |
Top Pathways | PI3K-Akt signaling pathway |
TCL-1B CRISPR/Cas9 KO Plasmid (h) - sc-407297 from Santa Cruz Biotechnology
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TCL-1B HDR Plasmid (h) - sc-407297-HDR from Santa Cruz Biotechnology
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TCL-1B Double Nickase Plasmid (h) - sc-407297-NIC from Santa Cruz Biotechnology
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TCL-1B Double Nickase Plasmid (h2) - sc-407297-NIC-2 from Santa Cruz Biotechnology
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TCL-1B CRISPR Activation Plasmid (h) - sc-407297-ACT from Santa Cruz Biotechnology
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TCL-1B CRISPR Activation Plasmid (h2) - sc-407297-ACT-2 from Santa Cruz Biotechnology
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TCL-1B Lentiviral Activation Particles (h) - sc-407297-LAC from Santa Cruz Biotechnology
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TCL-1B Lentiviral Activation Particles (h2) - sc-407297-LAC-2 from Santa Cruz Biotechnology
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TCL-1B siRNA (h) - sc-42990 from Santa Cruz Biotechnology
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TCL-1B shRNA Plasmid (h) - sc-42990-SH from Santa Cruz Biotechnology
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TCL-1B shRNA (h) Lentiviral Particles - sc-42990-V from Santa Cruz Biotechnology
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TCL1B RNAi - H00009623-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21157 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21157 from Sigma-Aldrich
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TCL1B siRNA (Human) - CRH6404 from Cohesion Biosciences
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TCL1B RNAi - H00009623-R01 from Novus Biologicals
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TCL1B - MBS8203218 from MyBioSource
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TCL-1B CRISPR/Cas9 KO Plasmid (h2) - sc-407297-KO-2 from Santa Cruz Biotechnology
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TCL-1B HDR Plasmid (h2) - sc-407297-HDR-2 from Santa Cruz Biotechnology
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Human TCL1B siRNA - orb266906 from Biorbyt
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TCL1B shRNA Plasmid (Human) - CHH6404 from Cohesion Biosciences
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