Gene Symbol | CFHR5 |
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Entrez Gene | 81494 |
Alt Symbol | CFHL5, CFHR5D, FHR-5, FHR5 |
Species | Human |
Gene Type | protein-coding |
Description | complement factor H-related 5 |
Other Description | complement factor H-related protein 5|factor H-related protein 5 |
Swissprots | Q2NKK2 Q9BXR6 |
Accessions | CBN73477 EAW91268 Q9BXR6 AF295327 AAK15619 AK314026 BAG36736 BC026282 AAH26282 BC111773 AAI11774 BG568555 DA638244 XM_011510020 XP_011508322 NM_030787 NP_110414 |
Function | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. {ECO:0000269|PubMed:23487775}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
FHR-5 CRISPR/Cas9 KO Plasmid (h) - sc-410165 from Santa Cruz Biotechnology
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FHR-5 HDR Plasmid (h) - sc-410165-HDR from Santa Cruz Biotechnology
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FHR-5 Double Nickase Plasmid (h) - sc-410165-NIC from Santa Cruz Biotechnology
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FHR-5 Double Nickase Plasmid (h2) - sc-410165-NIC-2 from Santa Cruz Biotechnology
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FHR-5 CRISPR Activation Plasmid (h) - sc-410165-ACT from Santa Cruz Biotechnology
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FHR-5 CRISPR Activation Plasmid (h2) - sc-410165-ACT-2 from Santa Cruz Biotechnology
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FHR-5 Lentiviral Activation Particles (h) - sc-410165-LAC from Santa Cruz Biotechnology
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FHR-5 Lentiviral Activation Particles (h2) - sc-410165-LAC-2 from Santa Cruz Biotechnology
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FHR-5 siRNA (h) - sc-88729 from Santa Cruz Biotechnology
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FHR-5 shRNA Plasmid (h) - sc-88729-SH from Santa Cruz Biotechnology
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FHR-5 shRNA (h) Lentiviral Particles - sc-88729-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU145181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6004 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6004 from Sigma-Aldrich
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CFHR5 siRNA (Human) - CRJ2978 from Cohesion Biosciences
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CFHR5 - MBS8204004 from MyBioSource
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shRNA set against Human CFHR5 (NM_030787.3) - SHH262461 from Creative biogene
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Human CFHR5 siRNA - orb273479 from Biorbyt
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CFHR5 shRNA Plasmid (Human) - CHJ2978 from Cohesion Biosciences
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CFHR5 miRNA 3'UTR clone - MiUTR1H-02075 from Creative biogene
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