| Gene Symbol |
BRI1
|
| Entrez Gene |
830095
|
| Alt Symbol |
ATBRI1, BIN1, BR INSENSITIVE 1, BRASSINOSTEROID INSENSITIVE 1, CABBAGE 2, CBB2, DWARF 2, DWF2, F23K16.30, F23K16_30
|
| Species |
Arabidopsis thaliana
|
| Gene Type |
protein-coding
|
| Description |
protein brassinosteroid insensitive 1
|
| Other Description |
-
|
| Swissprots |
O22476 C0LGS4
|
| Accessions |
AAC49810 AEE87069 CAB44675 CAB80603 O22476 FJ708766 ACN59359 NM_120100 NP_195650
|
| Function |
Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr- 462' in vitro. May have a guanylyl cyclase activity. {ECO:0000269|PubMed:10557222, ECO:0000269|PubMed:10938344, ECO:0000269|PubMed:17138891, ECO:0000269|PubMed:17520012, ECO:0000269|PubMed:18694562, ECO:0000269|PubMed:19124768}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Expressed ubiquitously. {ECO:0000269|PubMed:10938344, ECO:0000269|PubMed:9298904}.
|
| Top Pathways |
Plant hormone signal transduction
|