| Gene Symbol |
CCR2
|
| Entrez Gene |
729230
|
| Alt Symbol |
CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-C motif) receptor 2
|
| Other Description |
C-C chemokine receptor type 2|MCP-1 receptor|monocyte chemoattractant protein 1 receptor|monocyte chemotactic protein 1 receptor
|
| Swissprots |
Q4VBL2 A0AVQ3 P41597 B2RMT0
|
| Accessions |
AAB57791 AAB57792 AAC51636 AAC51637 AAN16400 ABW17216 ABW17217 AGC02842 AGC02843 AGC02844 AGC02845 AGC02846 AGC02847 AGC02848 AGC02849 AGC02850 AGC02851 CAD88094 EAW64760 EAW64761 EAW64762 P41597 AK292685 BAF85374 AK292920 BAF85609 AV715904 BC074751 AAH74751 BC095540 AAH95540 BC126452 AAI26453 BC136396 AAI36397 BQ027284 BX101672 D29984 BAA06253 DA927445 DC401093 DC418358 HQ258202 ADR82956 U03882 AAA19119 U03905 AAA19120 X95583 CAA64835 XM_011534069 XP_011532371 NM_001123041 NP_001116513 NM_001123396 NP_001116868
|
| Function |
Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. {ECO:0000269|PubMed:23408426}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:18587271}; Multi-pass membrane protein {ECO:0000269|PubMed:18587271}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|
![Western Blot: CCR2 Overexpression Lysate (Adult Normal) [NBL1-08889] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCR2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4891_CCR2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08889-img0002.jpg)