| Gene Symbol |
KIF15
|
| Entrez Gene |
56992
|
| Alt Symbol |
HKLP2, KNSL7, NY-BR-62
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 15
|
| Other Description |
kinesin-like 7|kinesin-like protein 2|kinesin-like protein 7|kinesin-like protein KIF15|serologically defined breast cancer antigen NY-BR-62
|
| Swissprots |
Q9H280 Q9NS87 Q69YL6 Q96JX7 Q17RV9
|
| Accessions |
EAW64724 Q9NS87 AB035898 BAB03309 AF308294 AAG48261 AK027816 BAB55389 AK098533 AK307674 AL832908 CAH10635 BC117174 AAI17175 BC143752 DR005852 XM_006713261 XP_006713324 XM_006713262 XP_006713325 XM_006713264 XP_006713327 XM_006713265 XP_006713328 XM_011533964 XP_011532266 XM_011548741 XP_011547043 XM_011548742 XP_011547044 XM_011548743 XP_011547045 XM_011548744 XP_011547046 XM_011548745 XP_011547047 XR_940475 XR_940476 XR_940477 XR_940478 XR_940479 XR_940480 XR_940481 XR_953190 XR_953191 XR_953192 XR_953193 XR_953194 XR_953195 XR_953196 NM_020242 NP_064627
|
| Function |
Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in testis, colon, thymus and in breast cancer. {ECO:0000269|PubMed:12747765}.
|