| Gene Symbol |
VCAN
|
| Entrez Gene |
1462
|
| Alt Symbol |
CSPG2, ERVR, GHAP, PG-M, WGN, WGN1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
versican
|
| Other Description |
chondroitin sulfate proteoglycan 2|chondroitin sulfate proteoglycan core protein 2|glial hyaluronate-binding protein|large fibroblast proteoglycan|versican core protein|versican proteoglycan
|
| Swissprots |
Q13010 P20754 Q9UNW5 P13611 Q9UCL9 Q13189 Q15123
|
| Accessions |
AAB24878 EAW95904 EAW95905 EAW95906 EAW95907 EAW95908 EAW95909 EAW95910 EAW95911 P13611 AA320958 AA426499 AA478645 AB209491 BAD92728 AF084545 AAD48545 AK296285 BAH12302 AK299770 BAH13124 AK307642 BC050524 AAH50524 BC172276 AAI72276 BP332680 BX641036 CAE46022 CN312093 D32039 BAA06801 DA361670 DB497892 DT217515 J02814 AAA36437 U16306 AAA65018 U26555 AAA67565 X15998 CAA34128 NM_001126336 NP_001119808 NM_001164097 NP_001157569 NM_001164098 NP_001157570 NM_004385 NP_004376
|
| Function |
May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.
|
| Top Pathways |
Cell adhesion molecules (CAMs)
|