Gene Symbol | P4HA2 |
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Entrez Gene | 8974 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | prolyl 4-hydroxylase, alpha polypeptide II |
Other Description | 4-PH alpha 2|4-PH alpha-2|C-P4Halpha(II)|collagen prolyl 4-hydroxylase alpha(II)|procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II|procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2|prolyl 4-hydroxylase subunit alpha-2 |
Swissprots | D3DQ86 D3DQ85 Q8WWN0 O15460 |
Accessions | CAC85688 CAC85689 EAW62341 EAW62342 EAW62343 EAW62344 EAW62345 EAW62346 EAW62347 EAW62348 O15460 AU117989 AY358970 AAQ89329 BC017062 AAH17062 BC025960 BC035813 AAH35813 BI758477 BX647924 CAI46066 DA544450 DQ892431 ABM83357 EU176519 ABW03320 U90441 AAB71339 XM_005272116 XP_005272173 XM_005272117 XP_005272174 XM_005272118 XP_005272175 XM_005272119 XP_005272176 XM_005272120 XP_005272177 XM_006714728 XP_006714791 XM_006714729 XP_006714792 XM_006714730 XP_006714793 XM_011543705 XP_011542007 NM_001017973 NP_001017973 NM_001017974 NP_001017974 NM_001142598 NP_001136070 NM_001142599 NP_001136071 NM_004199 NP_004190 |
Function | Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. |
Subcellular Location | Endoplasmic reticulum lumen. |
Top Pathways | Arginine and proline metabolism |
P4HA2 CRISPR/Cas9 KO Plasmid (h) - sc-405566 from Santa Cruz Biotechnology
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P4HA2 HDR Plasmid (h) - sc-405566-HDR from Santa Cruz Biotechnology
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P4HA2 Double Nickase Plasmid (h) - sc-405566-NIC from Santa Cruz Biotechnology
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P4HA2 Double Nickase Plasmid (h2) - sc-405566-NIC-2 from Santa Cruz Biotechnology
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P4HA2 CRISPR Activation Plasmid (h) - sc-405566-ACT from Santa Cruz Biotechnology
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P4HA2 CRISPR Activation Plasmid (h2) - sc-405566-ACT-2 from Santa Cruz Biotechnology
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P4HA2 Lentiviral Activation Particles (h) - sc-405566-LAC from Santa Cruz Biotechnology
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P4HA2 Lentiviral Activation Particles (h2) - sc-405566-LAC-2 from Santa Cruz Biotechnology
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P4HA2 siRNA (h) - sc-92052 from Santa Cruz Biotechnology
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P4HA2 shRNA Plasmid (h) - sc-92052-SH from Santa Cruz Biotechnology
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P4HA2 shRNA (h) Lentiviral Particles - sc-92052-V from Santa Cruz Biotechnology
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P4HA2 RNAi - H00008974-R02 from Novus Biologicals
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P4HA2 RNAi - H00008974-R03 from Novus Biologicals
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P4HA2 RNAi - H00008974-R01 from Novus Biologicals
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MISSION® esiRNA - EHU082521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16239 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16239 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03760 from Sigma-Aldrich
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P4HA2 siRNA (Human) - CRH5924 from Cohesion Biosciences
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shRNA set against Human P4HA2 (NM_004199.2) - SHH369652 from Creative biogene
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shRNA set against Human P4HA2(NM_001017973.1) - SHR076918 from Creative biogene
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shRNA set against Human P4HA2(NM_004199.2) - SHR076954 from Creative biogene
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Human P4HA2 siRNA - orb266426 from Biorbyt
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P4HA2 shRNA Plasmid (Human) - CHH5924 from Cohesion Biosciences
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P4HA2 miRNA 3'UTR clone - MiUTR1H-07449 from Creative biogene
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