| Gene Symbol |
ROBO4
|
| Entrez Gene |
54538
|
| Alt Symbol |
ECSM4, MRB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
roundabout, axon guidance receptor, homolog 4 (Drosophila)
|
| Other Description |
roundabout homolog 4|roundabout homolog 4, magic roundabout
|
| Swissprots |
Q8WZ75 Q8TEG1 Q14DU7 Q9NWJ8 A8K154 Q9H718 Q96JV6
|
| Accessions |
EAW67610 EAW67611 EAW67612 EAW67613 Q8WZ75 AF361473 AAL31867 AK000805 BAA91382 AK025195 BAB15082 AK027852 BAB55411 AK074163 BAB84989 AK289769 BAF82458 AK297845 BAG60179 AK302628 BAG63870 AY358083 AAQ88450 BC014995 BC025675 BC039602 AAH39602 BC064643 AAH64643 BC111562 AAI11563 BC111748 AAI11749 DC424813 XM_006718861 XP_006718924 XM_011542875 XP_011541177 NM_001301088 NP_001288017 NM_019055 NP_061928
|
| Function |
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types. {ECO:0000269|PubMed:11944987}.
|
![Western Blot: Robo4 Overexpression Lysate (Adult Normal) [NBL1-15473] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Robo4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4589_Robo4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15473-img0002.jpg)