Gene Symbol | DNAH12 |
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Entrez Gene | 201625 |
Alt Symbol | DHC3, DLP12, DNAH12L, DNAH7L, DNAHC12, DNAHC3, DNHD2, HDHC3, HL-19, HL19 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, axonemal, heavy chain 12 |
Other Description | axonemal beta dynein heavy chain 12|axonemal dynein heavy chain isotype3|ciliary dynein heavy chain 12|dynein heavy chain 12, axonemal|dynein heavy chain domain-containing protein 2|dynein, axonemal, heavy polypeptide 12|dynein, heavy chain-5 |
Swissprots | Q8WXK2 A6NGI2 Q6ZR08 Q92816 Q8N7R9 Q6ZTR8 |
Accessions | AAB82762 EAW65339 EAW65340 EAW65341 Q6ZR08 AK097746 BAC05158 AK126276 BAC86512 AK128592 BAC87517 CD684932 CD708076 U53532 AAB09729 U61739 AAC50703 Z83802 CAB06056 XM_011533466 XP_011531768 XM_011533467 XP_011531769 XM_011533468 XP_011531770 XM_011533469 XP_011531771 XM_011533470 XP_011531772 XM_011533471 XP_011531773 XM_011533472 XP_011531774 XM_011533473 XP_011531775 XM_011533474 XP_011531776 NM_178504 NM_001291661 NP_001278590 NM_198564 NP_940966 |
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}. |
Top Pathways | Huntington's disease |
DNHD2 CRISPR/Cas9 KO Plasmid (h) - sc-415018 from Santa Cruz Biotechnology
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DNHD2 HDR Plasmid (h) - sc-415018-HDR from Santa Cruz Biotechnology
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DNHD2 Double Nickase Plasmid (h) - sc-415018-NIC from Santa Cruz Biotechnology
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DNHD2 Double Nickase Plasmid (h2) - sc-415018-NIC-2 from Santa Cruz Biotechnology
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DNHD2 CRISPR Activation Plasmid (h) - sc-415018-ACT from Santa Cruz Biotechnology
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DNHD2 CRISPR Activation Plasmid (h2) - sc-415018-ACT-2 from Santa Cruz Biotechnology
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DNHD2 Lentiviral Activation Particles (h) - sc-415018-LAC from Santa Cruz Biotechnology
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DNHD2 Lentiviral Activation Particles (h2) - sc-415018-LAC-2 from Santa Cruz Biotechnology
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DNAH12 siRNA (h) - sc-78218 from Santa Cruz Biotechnology
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DNAH12 shRNA Plasmid (h) - sc-78218-SH from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU087321 from Sigma-Aldrich
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MISSION® esiRNA - EHU091881 from Sigma-Aldrich
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MISSION® esiRNA - EHU098241 from Sigma-Aldrich
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MISSION® esiRNA - EHU100041 from Sigma-Aldrich
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MISSION® esiRNA - EHU064701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7329 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7329 from Sigma-Aldrich
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DNAH12 siRNA (Human) - CRJ6299 from Cohesion Biosciences
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DNAH12 - MBS8230849 from MyBioSource
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shRNA set against Human DNAH12 (NM_198564.3) - SHH279081 from Creative biogene
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DNAH12 shRNA Plasmid (Human) - CHJ6299 from Cohesion Biosciences
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DNAH12 miRNA 3'UTR clone - MiUTR4H-TG02778 from Creative biogene
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