Gene Symbol | ELK3 |
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Entrez Gene | 2004 |
Alt Symbol | ERP, NET, SAP-2, SAP2 |
Species | Human |
Gene Type | protein-coding |
Description | ELK3, ETS-domain protein (SRF accessory protein 2) |
Other Description | ETS domain-containing protein Elk-3|ETS-related protein ERP|ETS-related protein NET|SRF accessory protein 2|serum response factor accessory protein 2 |
Swissprots | Q9UD17 B2R6S6 Q6GU29 P41970 Q6FG57 |
Accessions | AAB34628 EAW97561 EAW97562 EAW97563 EAW97564 EAW97565 P41970 AK026078 AK312694 BAG35573 AL705041 AW575797 BC017371 AAH17371 CR542251 CAG47047 DA754301 DQ892954 ABM83880 DQ896201 ABM87200 Z36715 CAA85309 XM_006719275 XP_006719338 NM_001303511 NP_001290440 NM_005230 NP_005221 |
Function | May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element. |
Subcellular Location | Nucleus. |
Net CRISPR/Cas9 KO Plasmid (h) - sc-405945 from Santa Cruz Biotechnology
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Net HDR Plasmid (h) - sc-405945-HDR from Santa Cruz Biotechnology
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Net Double Nickase Plasmid (h) - sc-405945-NIC from Santa Cruz Biotechnology
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Net Double Nickase Plasmid (h2) - sc-405945-NIC-2 from Santa Cruz Biotechnology
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Net CRISPR Activation Plasmid (h) - sc-405945-ACT from Santa Cruz Biotechnology
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Net CRISPR Activation Plasmid (h2) - sc-405945-ACT-2 from Santa Cruz Biotechnology
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Net Lentiviral Activation Particles (h) - sc-405945-LAC from Santa Cruz Biotechnology
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Net Lentiviral Activation Particles (h2) - sc-405945-LAC-2 from Santa Cruz Biotechnology
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Net siRNA (h) - sc-37867 from Santa Cruz Biotechnology
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Net shRNA Plasmid (h) - sc-37867-SH from Santa Cruz Biotechnology
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Net shRNA (h) Lentiviral Particles - sc-37867-V from Santa Cruz Biotechnology
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ELK3 RNAi - H00002004-R01 from Novus Biologicals
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MISSION® esiRNA - EHU021441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7807 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7807 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13018 from Sigma-Aldrich
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ELK3 siRNA (Human) - CRH1387 from Cohesion Biosciences
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ELK3 - MBS8218046 from MyBioSource
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shRNA set against Human Elk3 (NM_005230.2) - SHH285089 from Creative biogene
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shRNA set against Human ELK3(NM_005230.2) - SHH031385 from Creative biogene
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Net CRISPR/Cas9 KO Plasmid (h2) - sc-405945-KO-2 from Santa Cruz Biotechnology
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Net HDR Plasmid (h2) - sc-405945-HDR-2 from Santa Cruz Biotechnology
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Human ELK3 siRNA - orb261889 from Biorbyt
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ELK3 shRNA Plasmid (Human) - CHH1387 from Cohesion Biosciences
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ELK3 miRNA 3'UTR clone - MiUTR1H-03194 from Creative biogene
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