Gene Symbol | DNAH6 |
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Entrez Gene | 1768 |
Alt Symbol | DNHL1, Dnahc6, HL-2, HL2 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, axonemal, heavy chain 6 |
Other Description | axonemal beta dynein heavy chain 6|ciliary dynein heavy chain 6|dynein heavy chain 6, axonemal|dynein heavy chain-like 1|dynein, axonemal, heavy polypeptide 6 |
Swissprots | Q53QZ1 O95493 A0PJN9 Q96BL6 B5MEE0 Q9H5E1 Q8N1W6 Q92861 Q9H030 Q9C0G6 Q53TE5 B7ZL99 |
Accessions | AAX93108 AAX93115 AAY24108 EAW99556 EAW99557 Q9C0G6 AB051484 BAB21788 AB290165 BAG06719 AJ132086 CAA10559 AK027182 BAB15685 AK094676 BAC04400 AL512706 CAC21651 BC015442 AAH15442 BC104884 AAI04885 BC113424 AAI13425 BC117259 AAI17260 BC143365 BC143666 AAI43667 JF432885 ADZ16102 U61736 AAC50700 XM_006711956 XP_006712019 XM_011532649 XP_011530951 XM_011532650 XP_011530952 XM_011532651 XP_011530953 XM_011532652 XP_011530954 XM_011532653 XP_011530955 XM_011532654 XP_011530956 XM_011532655 XP_011530957 XM_011532656 XP_011530958 XM_011532657 XP_011530959 XM_011532658 XP_011530960 XM_011532659 XP_011530961 XM_011532660 XP_011530962 XM_011532661 XP_011530963 NM_173645 NM_001370 NP_001361 |
Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. |
Tissue Specificity | Detected in brain, testis and trachea. {ECO:0000269|PubMed:11175280}. |
Top Pathways | Huntington's disease |
DNAH6 CRISPR/Cas9 KO Plasmid (h) - sc-409605 from Santa Cruz Biotechnology
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DNAH6 HDR Plasmid (h) - sc-409605-HDR from Santa Cruz Biotechnology
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DNAH6 Double Nickase Plasmid (h) - sc-409605-NIC from Santa Cruz Biotechnology
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DNAH6 Double Nickase Plasmid (h2) - sc-409605-NIC-2 from Santa Cruz Biotechnology
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DNAH6 CRISPR Activation Plasmid (h) - sc-409605-ACT from Santa Cruz Biotechnology
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DNAH6 CRISPR Activation Plasmid (h2) - sc-409605-ACT-2 from Santa Cruz Biotechnology
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DNAH6 Lentiviral Activation Particles (h) - sc-409605-LAC from Santa Cruz Biotechnology
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DNAH6 Lentiviral Activation Particles (h2) - sc-409605-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7334 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7334 from Sigma-Aldrich
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DNAH6 siRNA (Human) - CRH1228 from Cohesion Biosciences
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DNAH6 - MBS828779 from MyBioSource
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shRNA set against Human DNAH6 (NM_001370.1) - SHH279125 from Creative biogene
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Human DNAH6 siRNA - orb261730 from Biorbyt
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DNAH6 shRNA Plasmid (Human) - CHH1228 from Cohesion Biosciences
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DNAH6 miRNA 3'UTR clone - MiUTR3H-05871 from Creative biogene
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