Gene Symbol | DCT |
---|---|
Entrez Gene | 1638 |
Alt Symbol | TRP-2, TYRP2 |
Species | Human |
Gene Type | protein-coding |
Description | dopachrome tautomerase |
Other Description | DT|L-dopachrome Delta-isomerase|L-dopachrome tautomerase|TRP2|dopachrome delta-isomerase|dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)|tyrosinase-related protein 2|tyrosine-related protein 2 |
Swissprots | P40126 Q09GT4 |
Accessions | AAC41925 ABG82045 ABG82046 ABG82047 ABG82048 ABG82049 ABG82050 ABG82051 ABG82052 ABG82053 ABG82054 ABG82055 ABG82056 ABG82057 ABG82058 ABG82059 ABG82060 ABG82061 ABG82062 ABG82063 ABG82064 ABG82065 ABG82066 ABG82067 ABG82068 ABG82069 ABG82070 ABG82071 ABG82072 ABG82073 ABG82074 ABG82075 ABG82076 ABG82077 ABG82078 ABG82079 ABG82080 ABG82081 ABG82082 ABG82083 ABG82084 ABG82085 ABG82086 ABG82087 ABG82088 ABG82089 ABG82090 ABG82091 ABG82092 ABG82093 ABG82094 ABG82095 ABG82096 ABG82097 ABG82098 ABG82099 ABG82100 ABG82101 ABG82102 ABG82103 ABG82104 ABG82105 ABG82106 ABG82107 ABG82108 ABG82109 ABG82110 ABG82111 ABG82112 ABG82113 ABG82114 ABG82115 ABG82116 ABG82117 ABG82118 ABG82119 ABG82120 ABG82121 ABG82122 ABG82123 ABG82124 ABG82125 ABG82126 ABG82127 ABG82128 ABG82129 ABG82130 ABG82131 ABG82132 ABG82133 ABG82134 ABG82135 ABG82136 ABG82137 ABG82138 ABG82139 ABG82140 ABG82141 ABG82142 ABG82143 ABG82144 ABG82145 ABG82146 ABG82147 ABG82148 ABG82149 ABG82150 ABG82151 ABG82152 ABG82153 ABG82154 ABG82155 ABG82156 ABG82157 ABG82158 ABG82159 ABG82160 BAA05956 EAX08937 EAX08938 EAX08939 P40126 AF339808 AJ000503 CAA04137 AJ132932 CAB93530 AJ132933 CAB93531 AK293115 BAF85804 BC028311 AAH28311 BC104476 BP221841 D17547 BAA04484 DQ891466 ABM82392 DQ894649 ABM85575 DQ902581 ABI73976 L18967 AAA20870 S69231 AAC60627 XM_011521049 XP_011519351 XM_011521050 XP_011519352 XR_931610 NM_001129889 NP_001123361 NM_001922 NP_001913 |
Function | Involved in regulating eumelanin and phaeomelanin levels. |
Subcellular Location | Melanosome membrane {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}; Single-pass type I membrane protein {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}. |
Top Pathways | Melanogenesis, Tyrosine metabolism |
TRP2 CRISPR/Cas9 KO Plasmid (h) - sc-400334 from Santa Cruz Biotechnology
|
||||||||
TRP2 HDR Plasmid (h) - sc-400334-HDR from Santa Cruz Biotechnology
|
||||||||
TRP2 Double Nickase Plasmid (h) - sc-400334-NIC from Santa Cruz Biotechnology
|
||||||||
TRP2 Double Nickase Plasmid (h2) - sc-400334-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TRP2 CRISPR Activation Plasmid (h) - sc-400334-ACT from Santa Cruz Biotechnology
|
||||||||
TRP2 CRISPR Activation Plasmid (h2) - sc-400334-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TRP2 Lentiviral Activation Particles (h) - sc-400334-LAC from Santa Cruz Biotechnology
|
||||||||
TRP2 Lentiviral Activation Particles (h2) - sc-400334-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TRP2 siRNA (h) - sc-41661 from Santa Cruz Biotechnology
|
||||||||
TRP2 shRNA Plasmid (h) - sc-41661-SH from Santa Cruz Biotechnology
|
||||||||
TRP2 shRNA (h) Lentiviral Particles - sc-41661-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU048481 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN7001 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7001 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02239 from Sigma-Aldrich
|
||||||||
DCT siRNA (Human) - CRH1153 from Cohesion Biosciences
|
||||||||
TRP2 RNAi - H00001638-R01 from Novus Biologicals
|
||||||||
DCT - MBS8202074 from MyBioSource
|
||||||||
shRNA set against Human DCT (NM_001922.3) - SHH275333 from Creative biogene
|
||||||||
DCT shRNA Plasmid (Human) - CHH1153 from Cohesion Biosciences
|
||||||||
DCT miRNA 3'UTR clone - MiUTR3H-02335 from Creative biogene
|
||||||||
DCT miRNA 3'UTR clone - MiUTR3H-02336 from Creative biogene
|