| Gene Symbol |
KCNN1
|
| Entrez Gene |
3780
|
| Alt Symbol |
KCa2.1, SK1, SKCA1, hSK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
|
| Other Description |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1|small conductance calcium-activated potassium channel 1|small conductance calcium-activated potassium channel protein 1
|
| Swissprots |
Q92952 Q6DJU4 Q5KR10
|
| Accessions |
AAD37507 EAW84646 EAW84647 Q92952 AB198191 BAD86831 AK298170 BAG60442 AW594619 BC075037 AAH75037 BE504989 U69883 AAB09562 XM_005259905 XP_005259962 XM_005259906 XP_005259963 XM_005259907 XP_005259964 XM_011528004 XP_011526306 XM_011528005 XP_011526307 XR_244072 NM_002248 NP_002239
|
| Function |
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
![Western Blot: KCNN1 Overexpression Lysate (Adult Normal) [NBP2-04221] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNN1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4138_KCNN1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04221-img0001.jpg)