| Gene Symbol |
pomgnt2
|
| Entrez Gene |
497644
|
| Alt Symbol |
ago61, gtdc2, im:7153239, zgc:112079
|
| Species |
Zebrafish
|
| Gene Type |
protein-coding
|
| Description |
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
|
| Other Description |
glycosyltransferase|glycosyltransferase-like domain containing 2|glycosyltransferase-like domain-containing protein 2|protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
|
| Swissprots |
Q502K0 Q5NDE5
|
| Accessions |
Q5NDE5 AJ868539 CAI30873 BC095667 AAH95667 NM_001012384 NP_001012384
|
| Function |
O-linked mannose beta-1,4-N- acetylglucosaminyltransferase that tranfers UDP-N-acetyl-D- glucosamine to the 4-position of the mannose to generate N-acetyl- D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity). {ECO:0000250|UniProtKB:Q8NAT1}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8NAT1}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q8NAT1}.
|