SKI2

Gene Symbol SKI2
Entrez Gene 851114
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description SKI complex RNA helicase subunit SKI2
Other Description -
Swissprots D6VZ33 Q06047 P35207
Accessions DAA09699 P35207 NM_001182286 NP_013502
Function RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon. {ECO:0000269|PubMed:10611222, ECO:0000269|PubMed:10744028, ECO:0000269|PubMed:10922069, ECO:0000269|PubMed:11532933, ECO:0000269|PubMed:11720286, ECO:0000269|PubMed:12769863, ECO:0000269|PubMed:14671320, ECO:0000269|PubMed:363683, ECO:0000269|PubMed:6371496, ECO:0000269|PubMed:7739552, ECO:0000269|PubMed:7739557, ECO:0000269|PubMed:8321235, ECO:0000269|PubMed:9482746}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10744028, ECO:0000269|PubMed:14562095}.
Top Pathways RNA degradation

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