Gene Symbol | SKI2 |
---|---|
Entrez Gene | 851114 |
Alt Symbol | - |
Species | Yeast |
Gene Type | protein-coding |
Description | SKI complex RNA helicase subunit SKI2 |
Other Description | - |
Swissprots | D6VZ33 Q06047 P35207 |
Accessions | DAA09699 P35207 NM_001182286 NP_013502 |
Function | RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for cell growth only in the presence of M1 replicon. {ECO:0000269|PubMed:10611222, ECO:0000269|PubMed:10744028, ECO:0000269|PubMed:10922069, ECO:0000269|PubMed:11532933, ECO:0000269|PubMed:11720286, ECO:0000269|PubMed:12769863, ECO:0000269|PubMed:14671320, ECO:0000269|PubMed:363683, ECO:0000269|PubMed:6371496, ECO:0000269|PubMed:7739552, ECO:0000269|PubMed:7739557, ECO:0000269|PubMed:8321235, ECO:0000269|PubMed:9482746}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10744028, ECO:0000269|PubMed:14562095}. |
Top Pathways | RNA degradation |
Recombinant Saccharomyces cerevisiae Antiviral helicase SKI2(SKI2) ,partial - CSB-YP327406SVG CSB-EP327406SVG CSB-BP327406SVG CSB-MP327406SVG from Cusabio
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Antiviral helicase SKI2(SKI2) ,partial, Recombinant Protein - MBS1201131 from MyBioSource
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