Gene Symbol | EGR2 |
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Entrez Gene | 1959 |
Alt Symbol | AT591, CMT1D, CMT4E, KROX20 |
Species | Human |
Gene Type | protein-coding |
Description | early growth response 2 |
Other Description | E3 SUMO-protein ligase EGR2|KROX-20, Drosophila, homolog (early growth response-2)|early growth response protein 2|zinc finger protein Krox-20 |
Swissprots | B2R724 Q68CZ5 P11161 Q8IV26 B3KRD7 Q9UNA6 |
Accessions | CAH05293 CAH05295 CBX47619 EAW54238 EAW54239 P11161 AF139463 AAD24588 AK091399 BAG52349 AK296830 BAG59400 AK312813 BAG35671 BC035625 AAH35625 CD370447 CR749641 CAH18435 DA581108 DB242561 J04076 AAA52372 XM_011539427 XP_011537729 XM_011539428 XP_011537730 XM_011539429 XP_011537731 NM_000399 NP_000390 NM_001136177 NP_001129649 NM_001136178 NP_001129650 NM_001136179 NP_001129651 |
Function | Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. {ECO:0000269|PubMed:21836637}. |
Subcellular Location | Nucleus. |
Top Pathways | HTLV-I infection, Viral carcinogenesis |
Egr-2 CRISPR/Cas9 KO Plasmid (h) - sc-401203 from Santa Cruz Biotechnology
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Egr-2 HDR Plasmid (h) - sc-401203-HDR from Santa Cruz Biotechnology
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Egr-2 Double Nickase Plasmid (h) - sc-401203-NIC from Santa Cruz Biotechnology
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Egr-2 Double Nickase Plasmid (h2) - sc-401203-NIC-2 from Santa Cruz Biotechnology
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Egr-2 CRISPR Activation Plasmid (h) - sc-401203-ACT from Santa Cruz Biotechnology
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Egr-2 CRISPR Activation Plasmid (h2) - sc-401203-ACT-2 from Santa Cruz Biotechnology
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Egr-2 Lentiviral Activation Particles (h) - sc-401203-LAC from Santa Cruz Biotechnology
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Egr-2 Lentiviral Activation Particles (h2) - sc-401203-LAC-2 from Santa Cruz Biotechnology
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Egr-2 siRNA (h) - sc-37827 from Santa Cruz Biotechnology
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Egr-2 shRNA Plasmid (h) - sc-37827-SH from Santa Cruz Biotechnology
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Egr-2 shRNA (h) Lentiviral Particles - sc-37827-V from Santa Cruz Biotechnology
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EGR2 RNAi - H00001959-R01 from Novus Biologicals
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MISSION® esiRNA - EHU124311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7717 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7717 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12542 from Sigma-Aldrich
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EGR2 siRNA (Human) - CRH1355 from Cohesion Biosciences
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EGR2 - MBS8234247 from MyBioSource
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Egr-2 CRISPR/Cas9 KO Plasmid (h2) - sc-401203-KO-2 from Santa Cruz Biotechnology
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Egr-2 HDR Plasmid (h2) - sc-401203-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human EGR2 (NM_000399.3) - SHH283913 from Creative biogene
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EGR2 shRNA Plasmid (Human) - CHH1355 from Cohesion Biosciences
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EGR2 miRNA 3'UTR clone - MiUTR3H-00693 from Creative biogene
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EGR2 miRNA 3'UTR clone - MiUTR3H-00694 from Creative biogene
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EGR2 miRNA 3'UTR clone - MiUTR3H-00695 from Creative biogene
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