Gene Symbol |
KRTAP19-3
|
Entrez Gene |
337970
|
Alt Symbol |
GTRHP, KAP19.3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
keratin associated protein 19-3
|
Other Description |
GTHRP|glycine/tyrosine-rich protein|keratin-associated protein 19-3
|
Swissprots |
Q7Z4W3
|
Accessions |
EAX09897 Q7Z4W3 AB096944 BAE46359 AF139541 AAP97270 BC126280 BC126282 BC148585 AAI48586 BC148791 AAI48792 NM_181609 NP_853640
|
Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|