| Gene Symbol |
BOK
|
| Entrez Gene |
666
|
| Alt Symbol |
BCL2L9, BOKL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCL2-related ovarian killer
|
| Other Description |
bcl-2-like protein 9|bcl-2-related ovarian killer protein|bcl2-L-9|hBOK
|
| Swissprots |
Q9UMX3
|
| Accessions |
AAY14684 AAY14917 EAW71268 EAW71269 EAW71270 EAW71271 EAW71272 EAW71273 EAW71274 Q9UMX3 AF174487 AAD51719 BC006203 BC017214 BG118500 BI550157 BP332256 BT007272 AAP35936 BU855574 BX372066 BX395656 BX460019 CD368092 CN279174 CN279175 DQ893241 ABM84167 DQ896571 ABM87570 H17007 XM_005247037 XP_005247094 XM_005247039 XP_005247096 XM_011511696 XP_011509998 XM_011511697 XP_011509999 NM_032515 NP_115904
|
| Function |
Induces apoptosis in a manner dependent on BAX and BAK. {ECO:0000269|PubMed:23429263}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:23429263}; Single-pass membrane protein {ECO:0000269|PubMed:23429263}. Golgi apparatus membrane {ECO:0000269|PubMed:23429263}; Single-pass membrane protein {ECO:0000255}. Note=The transmembrane domain is necessary and sufficient for Golgi and ER targeting. {ECO:0000269|PubMed:23429263}.
|
| Tissue Specificity |
Expressed in brain, liver, appendix and lymphoid tissues. {ECO:0000269|PubMed:9535847}.
|