Gene Symbol |
FKBP3
|
Entrez Gene |
2287
|
Alt Symbol |
FKBP-25, FKBP-3, FKBP25, PPIase
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
FK506 binding protein 3, 25kDa
|
Other Description |
25 kDa FK506-binding protein|25 kDa FKBP|FK506-binding protein 25, T-cell|FK506-binding protein 3 (25kD)|PPIase FKBP3|immunophilin FKBP25|peptidyl-prolyl cis-trans isomerase FKBP3|rapamycin binding protein|rapamycin-selective 25 kDa immunophilin|rotamase
|
Swissprots |
Q14317 B2R4Q9 Q00688
|
Accessions |
EAW65785 Q00688 AK222993 BAD96713 AK311915 BAG34856 BC016288 AAH16288 BC020809 AAH20809 BI598048 BT006904 AAP35550 CN315192 DQ890734 ABM81660 DQ891132 ABM82058 DQ893906 ABM84832 DQ894311 ABM85237 M96256 AAA58471 XM_011536565 XP_011534867 NM_002013 NP_002004
|
Function |
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
|
Subcellular Location |
Nucleus.
|